Ethnic Specificities of S100B Protein Blood Level in Guadeloupe: Cross-sectional Study in Healthy Subjects

Conditions100b
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorCentre Hospitalier Universitaire de la Guadeloupe

About this trial

Numerous studies have demonstrated the significant contribution of S100B blood level measurement in the management of minor to moderate traumatic brain injuries, notably by reducing the number of cranial computed tomography (CT) scans by at least one-third. However, physiological blood concentrations of the S100B protein may be higher in individuals with a Black phenotype compared to those with Asian or, in particular, Caucasian phenotypes. Assessing S100B protein levels in healthy individuals will help confirm the variability of its physiological concentration according to skin phenotype.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Hospital staff of the University Hospital of Guadeloupe or the Hospital of Basse-Terre

Age between 18 and 65 years

Individuals willing to specify their ethnic origin and skin phototype

Individuals affiliated with or beneficiaries of a social security scheme

Disqualifiers

Individuals on anticoagulant therapy

Individuals with a personal history of neurological disease

Individuals with a personal history of melanoma

Refusal to participate

Trial population

Hospital staff of the University Hospital of Guadeloupe or the Basse-Terre Hospital

Trial design

Design model

Other

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

S100B and ethnicity

Level of S100B protein expressed in μg / L, which will be compared according to 3 groups: Afro-Caribbean, Indo-Caribbean and Caucasian.

Time frame
baseline

Secondary outcomes

1

S100B and phototypes

Level of S100B protein expressed in μg / L studied according to the 6 phototypes of Fitzpatrick classification.

Time frame
baseline

Other outcomes

Sponsors and contacts

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