EUS-Guided ATI and SWE in Individuals With Normal FibroScan

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAsian Institute of Gastroenterology, India

About this trial

The goal of this observational study is to establish preliminary reference values for Endoscopic Ultrasound (EUS)-guided Attenuation Imaging (ATI) and Shear Wave Elastography (SWE) in adults undergoing diagnostic EUS for non-hepatobiliary indications who have normal FibroScan findings. The main questions it aims to answer are:

What are the preliminary normal reference values for EUS-guided ATI in the right and left hepatic lobes? What are the preliminary normal reference values for EUS-guided SWE elasticity (kPa) and velocity (m/s) in the right and left hepatic lobes?

Participants will:

Undergo same-day FibroScan assessment to confirm normal liver stiffness and steatosis parameters.

Undergo EUS-guided ATI and SWE measurements of both the right and left hepatic lobes during their clinically indicated diagnostic EUS examination.

Have demographic, clinical, and laboratory information recorded for analysis.

Eligibility criteria

Qualifiers

Adults aged 18 years or older.

Undergoing clinically indicated diagnostic endoscopic ultrasound (EUS).

Same-day FibroScan examination available.

Controlled Attenuation Parameter (CAP) <238 dB/m.

Disqualifiers

Known chronic liver disease.

Hepatitis B or Hepatitis C infection.

Significant alcohol consumption.

Decompensated cirrhosis.

Trial design

Treatments tested in this trial

  • Endoscopic Ultrasound (EUS)
  • EUS-guided Attenuation Imaging (ATI)
  • EUS-Guided Shear Wave Elastography (SWE)
  • FibroScan

Treatment groups

100 Participants
are divided into 1 treatment group