Evaluate the Evolution of Body and Scalp Skin Discomfort in Patients With Hereditary Ichthyosis After Wraps (EnvelopIchtyose)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15+
SponsorUniversity Hospital, Toulouse

About this trial

Ichthyosis is a group of rare and chronic genetic diseases beginning at birth, in which the patient's skin is covered with scales of variable appearance and severity. This disease is disabling. The treatment is symptomatic and is based on the daily application of moisturizing creams with a high lipid content. Nevertheless, the effectiveness of these treatments is limited and are considered very painful by the patients. Wraps are local treatments carried out by specialized nurses and which consist in, following a therapeutic bath, applying a large quantity of cream to the whole body, followed by an occlusion. This type of care is simple to perform, but requires nursing expertise, to date, it is not carried out in standard practice in France, which is why the investigateur wish to evaluate the effect of wraps on different parameters reflecting the skin condition in the short and medium term.

Eligibility criteria

Qualifiers

Patient with hereditary ichthyosis regardless of the clinical form

Patient with a scaling or erythema score > 6/16

Patient with a skin discomfort score > 3/10

Patient having given written, free and informed consent

Disqualifiers

Patient with a skin disease other than ichthyosis

Patient having modified his treatments for ichthyosis in the month preceding inclusion

Patient with known intolerance or allergy to one of the topicals used in the study

Patient unable to complete the study questionnaires

Trial design

Treatments tested in this trial

  • Cutaneous wraps

Treatment groups

34 Participants
are divided into 1 treatment group

Sponsors and collaborators