Evaluating the Influence of 3D Culture Dish Design on Preimplantation Genetic Development in Sibling Oocytes: A Randomized Trial
Female patients aged 35 years or younger
A minimum of 15 mature oocytes available for ICSI
Classified as a good prognosis patient
Cases with severe DNA fragmentation
Patients undergoing FNA or TESE procedures
Severe male factor infertility
History of low or failed fertilization in previous cycles
Parallel
Microdrop GPS dish
DeviceThe µDrop GPS® micro-wells dish is specifically designed for oocyte and embryo handling and culture. The sloped concave micro-well bottoms of the µDrop GPS® dish allow oocytes and embryos to settle at a central location away from the well walls. The concave nature of the wells provides the thinnest well bottom possible, helping to reduce refraction and allow for optimal visualization. The wells may reduce droplet collapsing/mixing, offer better orientation/optics, and reduce set-up/observation time.
16 well BIRR dish
DeviceThe 16-Well BIRR Dish is a high-quality 3D culture dish designed for optimal embryo handling and identification in IVF. It features well-numbering (1-16) for clear tracking, a large labeling area, and an expanded working space for better accessibility. Its 16 wells allow for increased wash drops and single embryo culture, reducing the number of dishes needed per IVF cycle. Rigorously tested (MEA+, LAL, and SMA per lot), it ensures safe and efficient embryo culture.
Blastocyst Development rate
Defined as the proportion of blastocysts formed on day 5 or 6
Fertilization rate
Defined as the proportion of fertilized oocytes
Cleavage rate
Defined as the proportion of cleaved embryos on day 3
Blastocyst Quality rate
Defined as the assessment of blastocyst quality according to Gardner's criteria into: good, fair or poor
High Quality Day 3 rate
proportion of high quality day 3 embryos
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