Health TrialsbyHealthPanel

Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

ConditionDupuytren Contracture
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMohamed Maher Ismail Ahmed Elashmawy

About this trial

This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Participants diagnosed with Dupuytren's Contracture.

Willing to undergo ultrasound-guided needle knife dissection

Disqualifiers

Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.

Active hand infections, open wounds, or dermatological conditions in the treatment area.

Coagulopathy or use of anticoagulant that cannot be safely paused

Neuromuscular disorders affecting hand function

Trial design

Design model

Single group

Treatments tested in this trial

  • Ultrasound guided needle knife dissection

    Procedure/Surgery

    This procedure involves a minimally invasive dissection of the fibrous cords in Dupuytren's Contracture using a needle knife guided by ultrasound imaging. Local anesthesia using 3-5 ml of 1% Lidocaine and 0.25% bupivacaine is administered for patient comfort. The technique aims to improve precision, minimize complications and reduce recurrence. Device: Sonosite M-Turbo Ultrasound Machine with Linear Probe HFL38x (6-13 MHz) is used for real-time imaging during the procedure.

Treatment groups

30 Participants
are divided into 1 treatment group
Group A: Intervention Group: Ultrasound-Guided Needle Knife DissectionExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Improvement in hand Function

Functional Improvement: \- Evaluated using the QuickDASH score (0-100 scale).

Time frame
6 months
2

Improvement in hand mobility

Range of Motion (ROM): \- Measurment of joint mobility in degrees at MCP and PIP joints by goniometer.

Time frame
6 months

Secondary outcomes

1

Patient Satisfaction

Evaluation of patient-reported satisfaction using a standardized questionnaire.

Time frame
6 months
2

Rate of procedure-related complications

Monitoring and documentation of procedure-related complications, including infection, nerve injury, and other adverse events.

Time frame
6 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mohamed Maher Ismail Ahmed Elashmawy

Lead sponsor

Mansoura University Hospital

Sponsor institution

Source ClinicalTrials.gov
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