Evaluation of a Prostate-Targeted PET Imaging System (P-PET) for Detecting Prostate Cancer

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
AgeNot listed
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

About this trial

The goal of this study is to evaluate the imaging capabilities of a new prostate-targeted PET system (P-PET) and determine whether it could be useful in detecting prostate cancer by comparing SOC whole body PET imaging. This pilot study will include adult men who have been diagnosed with or are suspected to have prostate cancer. Participants will undergo a standard-of-care PET/CT scan followed by an additional P-PET scan designed to provide detailed images of the prostate. The images from the two scans to assess how well the P-PET system can detect prostate cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Qualitative comparison of PET scans acquired by the P-PET vs. WB PET

Disqualifiers

Unable to comply with the length of scan time due to the study imaging.

Trial design

Design model

Single group

Treatments tested in this trial

  • Prostate-Targeted PET- Scan (P-PET).

    Diagnostic test

    Participants will undergo a prostate-targeted PET scan to detect prostate cancer. This research scan is performed after the standard-of-care PET scan to evaluate its imaging capability. While the radioisotope is still active.

Treatment groups

25 Participants
are divided into 1 treatment group
Group A: Standard-of-care PET Scan with Additional Dynamic and P-PET imaging.Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Qualitative comparison of PET scans acquired by the P-PET vs. WB PET

The primary outcome is the detection of prostate cancer lesions by the research prostate-targeted P-PET scan. Images from the P-PET scan will be compared to standard-of-care PET scan images to evaluate the sensitivity and clarity of the new imaging system in identifying cancerous lesions in the prostate.

Time frame
Baseline (Day1)

Secondary outcomes

1

Number of Prostate Lesions Detected by P-PET Compared with Standard-of-care Whole-Body PET

The number of pelvic lesions detected by P-PET in comparison with the number of lesions detected by standard-of-care whole body PET/CT.

Time frame
Baseline (Day 1)

Other outcomes

Sponsors and contacts

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