Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorHoly Family Hospital, Nazareth, Israel

About this trial

Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are particularly important during the critical period of mother-child bonding. Hemoglobin levels in the first 24 hours after delivery do not reflect the lowest point (nadir). The postpartum nadir occurs 48-72 hours after delivery due to the initial redistribution of plasma volume. The aim of this study was to examine whether postpartum ultrasound examination precedes laboratory test results in the diagnosis of anemia due to blood loss after cesarean section.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Women who delivered by a cesarean section.

Age over 18.

Fluent in Hebrew or Arabic.

Signed informed consent form.

Disqualifiers

Lack of consent or inability to provide informed consent.

Inability to perform a post-surgical ultrasound, such as post-surgery hospitalization in the intensive care unit.

Women with preoperative coagulation disorders.

Women whose clinical condition requires a post-cesarean ultrasound examination.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ultrasound

    Diagnostic test

    The purpose of the test is to diagnose and assess the amount of blood loss.

  • Standard care

    Other intervention

    Routine management

Treatment groups

276 Participants
are divided into 2 treatment groups
Group A: Ultrasound groupActive comparator 1 intervention
Group B: Standard care groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Hemoglobin drop of 2g% or more within 24 - 36 hours

The proportion of women with a decrease in Hb levels of over 2 g% identified within 24 hours of surgery in both groups.

Time frame
24 -72 hours

Secondary outcomes

1

HB levels after 48-72

Difference in average HB levels after 48-72 hours between the two study groups

Time frame
72 hours postpartum
2

Inferior Vena Cava (IVC) diameter

Measurement of IVC diameter during inspiration and expiration

Time frame
up to 72 hours postpartum
3

IVC collapsibility index

IVC expiration-IVC inspiration/IVC expiration

Time frame
up to 72 hours postpartum
4

Uterine walls diameter

Measured midway between the fundus and the cervix of the uterus

Time frame
up to 72 hours postpartum

Other outcomes

Sponsors and contacts

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