Evaluation of Chest Wall Motion Symmetry During Ventilation in Healthy Subjects by Optoelectronic Plethysmography

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age10-70
SponsorUniversité de Reims Champagne-Ardenne

About this trial

Pulmonary ventilation is the only macroscopically observable breathing step. The ventilatory mechanism has been extensively studied and knowledge of its operation is now well established. The thoraco-abdominal couple is generally considered as a homogeneous functional unit. The anatomical organization of the trunk is not symmetrical. The right lung receives 55% of the volume of air mobilized, the heart is usually lateralized to the left and exerts a mechanical stress on the left lung, the thoracic diaphragm is asymmetrical. The densities of the subdiaphragmatic viscera vary greatly between hollow organs (stomach, colon) and full organs (liver rate).

Conventional spirometry, the gold-standard reference method in ventilatory analysis, allows to measure the quantities of air mobilized at inspiration and expiration. This quantitative method does not provide information on the kinematics of the different areas of the thorax and abdomen involved during breathing.

Optoelectronic plethysmography (OEP) is a non-invasive technique for the analysis of the 3D motion of passive markers placed on the surface of the subject's chest, abdomen and back. This technique, validated as a reliable alternative to conventional spirometry, allows the combination of quantitative measurements of respiratory volumes with qualitative measurements of thoraco-abdominal kinematics. The OEP has the specificity of allowing to choose a segmentation of the trunk to analyze the kinematics of the different identified zones. The most commonly used method in research is segmentation into three compartments (pulmonary thoracic, abdominal and abdominal thoracic).

The OEP studies also suggested the use of segmentation in relation to the median plane of the body to compare the symmetry of the three compartments described above. This 6-compartment segmentation was rarely used in respiratory analysis to assess interventions such as surgery of pulmonary rehabilitation protocols. To our knowledge, there is no study in healthy subjects to assess the level of symmetry of pulmonary ventilation. This type of study is a fundamental preliminary step to be able to subsequently study the symmetry of the ventilatory kinematics in the case of pathologies giving deformities of the thorax, spine and abdomen (scoliosis for example).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

aged between 10 and 70

with no prior major cardiopulmonary surgical, traumatic or medical history

agreeing to participate in the study

Disqualifiers

A major medical cardiopulmonary history, or a history of surgery or trauma to the thorax, abdomen or spine.

A major medical cardiopulmonary history included any pathology requiring hospital treatment or allopathic therapy lasting more than 3 months.

Active smoker

Protected by law (guardianship, curatorship, safeguard of justice)

Trial population

The study population will consist of consenting healthy subjects over 10 years of age, with no major surgical, traumatic or medical cardiopulmonary antecedents.

Trial design

Design model

Case-only

Time perspective

Cross-sectional

Treatments tested in this trial

  • Data collection

    Other intervention

    Data collection

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: healthy subjects1 intervention

Trial outcomes

Primary outcomes

1

pulmonary ribcage asymmetry score

Opto-electronic plethysmography (OEP), using a 3D motion analysis system consisting of 8 optitrack FLEX 13 cameras and 93 passive markers placed on the thorax, abdomen and back of the subject, will assess the volume of all 6 compartments (pulmonary ribcage, abdominal ribcage and their subdivision into left and right parts). pulmonary chest asymmetry score will be the difference between the volume of pulmonary ribcage right and the volume of pulmonary ribcage left

Time frame
Day 0

Secondary outcomes

1

abdominal ribcage asymmetry score

Opto-electronic plethysmography (OEP), using a 3D motion analysis system consisting of 8 optitrack FLEX 13 cameras and 93 passive markers placed on the thorax, abdomen and back of the subject, will assess the volume of all 6 compartments (pulmonary ribcage, abdominal ribcage and right and left abdomen). abdominal chest asymmetry score will be the difference between the volume of abdominal ribcage right and the volume of abdominal ribcage left

Time frame
Day 0
2

abdominal ribcage asymmetry score

Opto-electronic plethysmography (OEP), using a 3D motion analysis system consisting of 8 optitrack FLEX 13 cameras and 93 passive markers placed on the thorax, abdomen and back of the subject, will assess the volume of all 6 compartments (pulmonary ribcage, abdominal ribcage and right and left abdomen). abdomen asymmetry score will be the difference between the volume of abdomen right and the volume of abdomen left

Time frame
Day 0

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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