Evaluation of Intercostal Neuralgia in Patients With Chest Tube Insertion After Traumatic Rib Fracture

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSunnybrook Health Sciences Centre

About this trial

Traumatic rib fractures are common injuries following blunt chest trauma, often requiring chest tube insertion to manage complications such as pneumothorax or haemothorax. However, chest tube placement can lead to intercostal nerve injury, resulting in intercostal neuralgia-a debilitating condition characterized by chronic, neuropathic pain along the intercostal nerves. Despite its clinical significance, the incidence, risk factors, and long-term outcomes of intercostal neuralgia in this patient population remain poorly understood.

Chronic pain following thoracic trauma, including intercostal neuralgia, has been shown to significantly impair quality of life and functional outcomes, leading to prolonged disability and increased healthcare utilization. Current literature highlights the need for better understanding and management of this condition, particularly in patients undergoing invasive procedures such as chest tube insertion. This study aims to prospectively evaluate the development of intercostal neuralgia in patients with chest tube insertion following traumatic rib fractures.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults (≥18 years) with traumatic rib fractures requiring chest tube insertion

Chest tube or pigtail insertion performed during their initial hospitalization for trauma

Disqualifiers

Patients with spinal cord injury

Inability to complete follow-up assessments (e.g., language barriers, lack of telephone access)

Patients with traumatic brain injury

Patients with spinal cord injury

Trial population

Patients with acute traumatic rib fractures requiring chest tube insertion for management.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Chest tube insertion

    Procedure/Surgery

    Insertion of chest tube

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: Chest tube inserted1 intervention

Trial outcomes

Primary outcomes

1

Incidence of intercostal neuralgia

To determine the incidence of intercostal neuralgia in patients undergoing chest tube insertion after traumatic rib fractures. Presence of neuropathic pain to be assessed using S-LANSS (score of 12 or more suggests pain of predominantly neuropathic origin)

Time frame
1 and 3 months

Secondary outcomes

1

Assess the impact of intercostal neuralgia on quality of life and functional outcomes

Assess the impact of intercostal neuralgia on quality of life using EQ-5D-5L (assesses 5 dimensions, with 1 indicating 'no problems' and 5 indicating 'extreme problems')

Time frame
1 and 3 months
2

Assess the impact of intercostal neuralgia on quality of life and functional outcomes

Assess the impact of intercostal neuralgia on quality of life using Promis 6a Sleep questionnaire (scale 1 to 5, with higher numbers indicating poor outcomes and lower numbers indicating good outcomes)

Time frame
1 and 3 months
3

Assess the impact of intercostal neuralgia on medication use

Determine the impact of intercostal neuralgia on medication use including opioids and anti-neuropathic medications by collection and assessment of quantity of medications taken for pain relief related to intercostal neuralgia.

Time frame
1 and 3 months

Other outcomes

Sponsors and contacts

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