Left ventricular hypertrophy (LVH) is a common condition that may result from hypertension, hypertrophic cardiomyopathy, aortic valve stenosis, or certain metabolic disorders. Cardiac imaging is essential for diagnosis, prognostic assessment, and quantification of cardiac function. While transthoracic echocardiography remains widely used, it is limited by acoustic window dependence and inter-observer variability. Cardiovascular Magnetic Resonance (CMR) imaging currently serves as the reference standard for measuring left ventricular ejection fraction (LVEF), cardiac volumes, and tissue characterization. However, conventional cine-CMR sequences require repeated breath-holds, which are often challenging for elderly or dyspneic patients, generating respiratory motion artifacts that compromise image quality. Accelerated cine-CMR sequences with deep learning-based image reconstructions offer a promising alternative by significantly reducing acquisition time while preserving image quality. This study aims to evaluate whether these accelerated cine-CMR sequences provide LVEF measurements concordant with conventional cine-CMR sequences, with potential to improve patient comfort and reduce examination time.
Patient referred for cardiac MRI as part of the assessment or follow-up of left ventricular hypertrophy
Age ≥ 18 years old
Ability of the subject to understand and express his consent
Affiliation to the social security scheme
Severe obesity (>140 kg) preventing the patient from entering the scanner bore, which has a diameter of less than 70 cm
Age ≥ 18 years old
Person under guardianship or curators, or deprived of liberty
Pregnant or breastfeeding woman
Single group
accelerated cardiac cine-MRI sequence
Other interventionAddition of an accelerated cardiac cine-MRI sequence with deep learning-based image reconstruction to the standard cardiac MRI protocol, performed during the same session
LVEF Difference between both sequences
Value of the difference between the measurement of left ventricular ejection fraction (LVEF) obtained using the accelerated cardiac cine-MRI sequence with Deep Learning-based image reconstruction compared to the conventional cine-MRI sequence.
difference of end-diastolic volume of the left ventricle between both sequences
Value of the difference between the measurements of end-diastolic volumes of the left ventricle obtained using the accelerated cardiac cine-MRI sequence with Deep Learning-based image reconstruction compared to the conventional cine-MRI sequence.
difference of end-systolic volume of the left ventricle between both sequences
Value of the difference between the measurements of end-systolic volumes of the left ventricle obtained using the accelerated cardiac cine-MRI sequence with Deep Learning-based image reconstruction compared to the conventional cine-MRI sequence.
Differnce of measurement of the global longitudinal strain of the left ventricle between both sequences
Value of the difference between the measurement of global longitudinal strain of the left ventricle obtained using the accelerated cardiac cine-MRI sequence with Deep Learning-based image reconstruction compared to the conventional cine-MRI sequence.
Difference of the left ventricular mass between both sequences
Value of the difference between the measurement of left ventricular mass obtained using the accelerated cardiac cine-MRI sequence with Deep Learning-based image reconstruction compared to the conventional cine-MRI sequence.
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