The study aims to show that treatment with LtAPD works better than a sham treatment or simply monitoring the condition closely without active treatment ("active surveillance"), in achieving complete healing of a tissue abnormality on the cervix called CIN 2, after 6 months. This will be confirmed by examining tissue samples under a microscope (histopathological examination).
Female sex
Age 18 - 40 years at the time of signing the informed consent
Histologically confirmed CIN 2
Full visibility of the entire transformation zone (Type 1 or Type 2) and entire lesion in colposcopy
Histologically confirmed CIN other than CIN 2, or indication of (micro-) invasive cervical disease
CIN lesions extending to the vaginal vault or suspicion of endocervical disease
Current pregnancy or planned pregnancy within the next 6 months
Presence of severe local inflammation or active infection