Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-70
SponsorGulf Medical University

About this trial

An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft tissue thickness and increase the width of keratinized tissue around dental implants. The stability of the PRF membrane is maintained by securing it with the healing abutment of the implant. While a few longitudinal studies have assessed the benefits of using PRF membrane with Sohn's Poncho technique in the posterior region, its effectiveness in the anterior region of the mouth remains to be evaluated.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients with single bounded missing tooth in the esthetic zone Patients in the age group of 21-65 years Patients having good oral hygiene (mean plaque score of < 25%) and with stable periodontal status.

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Platelet rich fibrin multilayered Platelet-rich fibrin (PRF) A t the second stage

    Procedure/Surgery

    The test group will be treated with dental implant + multilayered PRF membrane. In brief, local anesthesia will be administered, and a crestal incision will be made to access the implant site. A full thickness mucoperiosteal flap will be reflected, exposing the underlying bone. The osteotomy will be performed following the implant manufacturer's guidelines, and a titanium implant will be placed at the planned position. For the purposes of standardization, implants will be placed at subcrestal level in both the groups. In the test group, at 4 months post-implant placement, a small incision will be made to place the healing abutment. Simple interrupted sutures will be used to approximate the tissues.

  • Soft tissue augmentation around dental implants with CTG in the second stage

    Procedure/Surgery

    The test group will be treated with dental implant and CTG. In brief, local anesthesia will be administered, and a crestal incision will be made to access the implant site. A full thickness mucoperiosteal flap will be reflected, exposing the underlying bone. The osteotomy will be performed following the implant manufacturer's guidelines, and a titanium implant will be placed at the planned position. For the purposes of standardization, implants will be placed at subcrestal level in both the groups. In the test group, at 4 months post-implant placement, a small incision will be made to place the healing abutment. Simple interrupted sutures will be used to approximate the tissues.

Treatment groups

26 Participants
are divided into 2 treatment groups
Group A: Experimental: Platelet rich fibrin multilayered Platelet-rich fibrin (PRF) is a second-generation auExperimental treatment 1 intervention
Group B: Active Comparator: Connective Tissue Graft gingival grafting surgery that is done to enhance soft tiActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Peri-implant soft tissue thickness

Volumetric

Time frame
Time Frame: 6 weeks and 3 and 6 months

Secondary outcomes

1

width of the keratinized tissue around dental implants

Periodontal probe mm

Time frame
Time Frame: baseline, 3 and 6 months
2

Marginal bone loss

CBCT measurement

Time frame
6 months
3

Postoperative patient satisfaction VAS 0-5

VAS 0-5

Time frame
baseline, 2 weeks, 6 months

Other outcomes

Sponsors and contacts

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