Evaluation of Recruitment Effectiveness in Patients With Obstructive Sleep Apnea Syndrome Using Lung Ultrasound

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorIstanbul University - Cerrahpasa

About this trial

Patients with obstructive sleep apnea syndrome are at higher risk for respiratory complications after surgery. Oxygen depletion and respiratory distress are common in patients with obstructive sleep apnea syndrome. In this study, the effectiveness of the recruitment maneuver applied in the postoperative period will be investigated via lung ultrasound. Recruitment is a technique performed to improve the oxygen levels of patients. Patients diagnosed with obstructive sleep apnea syndrome between the ages of 18-65 will be included in the study and anesthesia and surgical procedures will be followed. The aim of the study is to compare the pulmonary complication rates between patients who underwent recruitment and those who did not, and to examine the effects of factors such as age and gender on these complications via lung ultrasound.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18-65

American Society of Anesthesia I-III

Patients with consent to participate

Patients with preoperative OSA diagnosis (polysomnography or STOP-BANG≥3)

Disqualifiers

American Society of Anesthesia >IV

Patients planned for postoperative intensive care follow-up 3. Cardiac surgery

Anesthesia outside the operating room

History of neuromuscular disease

Trial design

Design model

Crossover

Treatments tested in this trial

  • Lung Recruitment Maneuver

    Other intervention

    Lung Recruitment Maneuver (LRM) is a method that allows the alveoli to reopen by applying high positive pressure in order to prevent or treat alveolar collapse (atelectasis) that develops during or after anesthesia. LRM improves oxygenation by increasing functional residual capacity. Clinical studies have shown that LRM increases oxygenation levels, reduces areas of atelectasis, and shortens hospital stay. In this study, the effects of different recruitment maneuvers on postoperative atelectasis will be evaluated. In this group, just before extubation, the patients in this group will be given 6 breaths with a tidal volume of 2 times the vital capacity, an inspiratory/expiratory ratio of 1/1 and a lung plateau pressure of \< 35 cmH2O, and a recruitment maneuver will be performed at the end of the surgery.

  • Positional Lung Recruitment Maneuver

    Other intervention

    Lung Recruitment Maneuver (LRM) is a method that allows the alveoli to reopen by applying high positive pressure in order to prevent or treat alveolar collapse (atelectasis) that develops during or after anesthesia. LRM improves oxygenation by increasing functional residual capacity. Clinical studies have shown that LRM increases oxygenation levels, reduces areas of atelectasis, and shortens the length of hospital stay. In this study, the effects of different recruitment maneuvers on postoperative atelectasis will be evaluated. Patients in this group will be placed in the right and then left lateral decubitus position before extubation at the end of surgery and a recruitment maneuver will be performed by giving 6 breaths in each position, with a tidal volume twice the vital capacity, a 1/1 inspiratory/expiratory ratio, and a lung plateau pressure \< 35 cmH2O.

Treatment groups

66 Participants
are divided into 3 treatment groups
Group A: Group 1- controlNo intervention 0 interventions
Group B: Group 2Active comparator 1 intervention
Group C: Group 3Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

pulmonary complications underwent recruitment maneuver

The primary outcome of the study was to compare the pulmonary complication rates between patients who underwent the recruitment maneuver and those who did not by lung ultrasound. Pulmonary complications were assessed by using the modified lung ultrasound score (LUSS). Higher scores on the LUSS indicated more severe ventilation loss. The degree of deaeration was assessed from 0 to 3. , Less than 3 B lines; ≥3 B lines were rated as 1, greater than 5 and confluent B lines were rated as 2, and multiple confluent B lines separated by a thickened or irregular pleural line or multiple subpleural consolidations were rated as 3.

Time frame
10 minutes before the start of surgery until 10 minutes after the end of surgery

Secondary outcomes

1

Pulmonary Complications with Different Recruitment Maneuver Techniques

The secondary outcome is to compare the pulmonary complication rates between patients who received different recruitment maneuver techniques. To compare the postoperative pulmonary complication rates of parameters such as age, gender, and body mass index. Pulmonary complications will be assessed by performing the modified lung ultrasound score (LUSS). Higher scores on the LUSS indicate more severe ventilation loss. The degree of deaeration will be assessed from 0 to 3. , Less than 3 B lines; ≥3 B lines indicate 1, greater than 5 and confluent B lines indicate 2, and multiple confluent B lines separated by thickened or irregular pleural lines or multiple subpleural consolidations indicate 3.

Time frame
10 minutes before the start of surgery until 10 minutes after the end of surgery

Other outcomes

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