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Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years

ConditionDyslexia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-9
SponsorInstitut Pasteur

About this trial

Studies of dyslexia have shown altered oscillatory activity in the low gamma band (\~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to form specific phonemic categories on which reading learning is based is derived. An alteration of the oscillatory activity at 30 Hz could therefore influence the ability of children to learn to read, and explain the reading deficit observed in children with a specific written language disorder. The objective of our study is to determine whether intensive rhythmic auditory stimulation applied during 30 sessions of 15 minutes spread over 6 weeks (5 sessions per week) can correct neural oscillations in the gamma-low band, allowing an improvement of phonemic categorization abilities, and thus the reading abilities of dyslexic readers aged 7 to 9 years. The long-term objective of this study is to test the therapeutic potential of auditory stimulation with speech rhythms for the treatment of reading disorders.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

between 7 and 9 years old

in regular schooling

have a diagnosis of dyslexia

have a non-verbal intelligence assessment within the norm. Inclusion assessments must show a major reading disability without associated cognitive deficits.

Disqualifiers

have any other diagnosis of language impairment

have a neurological disorder (visual, auditory, executive)

have an associated psychiatric disorder

have a developmental delay.

Trial design

Design model

Parallel

Treatments tested in this trial

  • behavioral measures

    Behavioral

    behavioral measures

  • Electrophysiological measures

    Other intervention

    Electrophysiological measures

  • Training 1

    Other intervention

    Training 1

  • Training 2

    Other intervention

    Training 2

Treatment groups

160 Participants
are divided into 4 treatment groups
Group A: Auditory Rhythmic at 30 Hz then GraphoGameOther 4 interventions
Group B: GraphoGame then Rhythmic Auditory at 30 HzOther 4 interventions
Group C: Auditory Rhythmic at low frequencies then GraphoGameOther 4 interventions
Group D: GraphoGame then Auditory Low Frequency RhythmicOther 4 interventions

Trial outcomes

Primary outcomes

1

Comparison of reading accuracy by measuring the percentage of correct responses in the isolated pseudoword reading task between rythmic auditory training condition vs. grapho-phonological mapping training (GraphoGame).

Comparison of reading performance is assessed in terms of both accuracy and speed. High percentage of correct responses means that children improve their reading accuracy.

Time frame
2 years
2

Comparison of reading speed by measuring reading time in the isolated pseudoword reading task between rythmic auditory training condition vs. grapho-phonological mapping training (GraphoGame).

Comparison of reading performance is assessed in terms of both accuracy and speed. A short time means that children improve their reading speed.

Time frame
2 years

Secondary outcomes

1

Measurement of reading accuracy (percentage of correct responses in the isolated pseudoword reading task) between multiple conditions.

Reading accuracy compared between rhythmic auditory training then grapho-phonological mapping training vs. grapho-phonological mapping training then rhythmic auditory training and rhythmic auditory training at 30 Hz vs. rhythmic auditory training at 3.5 Hz

Time frame
2 years
2

Measurement of reading speed (reading time in the isolated pseudoword reading task) between multiple conditions.

Reading speed compared between rhythmic auditory training then grapho-phonological mapping training vs. grapho-phonological mapping training then rhythmic auditory training and rhythmic auditory training at 30 Hz vs. rhythmic auditory training at 3.5 Hz

Time frame
2 years

Other outcomes

Sponsors and contacts

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Institut Pasteur

Lead sponsor

Institut de l'Audition

Collaborator

Source ClinicalTrials.gov
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