About this trial
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach. Data will be collected through validated questionnaires: OQLQ (Orthognathic Quality of Life Questionnaire), OHIP-14 (Oral Health Impact Profile), SF-36 (Medical Outcomes Study 36 - Item Short-Form Health Survey) and IOTN (Index of Orthodontic Treatment Need).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adults;
Skeletal malocclusion;
ANB Angle zero or negative;
Witts negative;
Disqualifiers
Previous orthodontic treatment;
Craniofacial anomaly or previous fracture of the facial bones;
Total edentulism;
Deep curve of Spee;
Trial design
Parallel
Treatments tested in this trial
Orthognathic Surgery
Procedure/SurgeryType of surgery performed to correct skeletal malocclusions
Treatment groups
Trial outcomes
Primary outcomes
Quality of life accessed by validated questionnaires.
Comparison between quality of life changes in the two groups at the end of treatment.
Secondary outcomes
Periodontal status.
Comparison between periodontal changes in the two groups at the end of the treatment.
Treatment duration.
Comparison between treatment time in the two groups at the end of the treatment.
Facial changes as measured by tomographic superimposition of the face.
Comparison between facial changes in the two groups at the end of the treatment.
Incisors inclination
Quantitative assessment of incisors inclination between the two groups as measured by tomographic superimposition at the end of orthodontic treatment.
Sponsors and contacts
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