Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Bordeaux

About this trial

Malnutrition is common at the time of diagnosis of esogastric cancers. However, there are no recommendations regarding preoperative nutritional support (type and duration) or on the impact of refeeding on postoperative morbidity and mortality.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient undergoing surgery for esophageal cancer

Malnourished patient at the time of management

Receiving neoadjuvant treatment

Disqualifiers

Patient not malnourished at the time of management

Patient who did not receive neoadjuvant treatment

Trial population

Retrospective case-control study including patients with esophageal cancer treated with neoadjuvant therapy. The control group consists of patients who did not receive enteral or parenteral nutrition during neoadjuvant treatment. The case group consists of patients who received enteral or parenteral nutrition during neoadjuvant treatment.

Trial design

Design model

Case-control

Time perspective

Retrospective

Treatments tested in this trial

  • Enteral or parenteral nutrition

    Dietary supplement

    Patients who did not receive enteral or parenteral nutrition during neoadjuvant treatment.

Treatment groups

670 Participants
are divided into 2 treatment groups
Group A: Control group0 interventions
Group B: Case group1 intervention

Trial outcomes

Primary outcomes

1

Rate of postoperative complications according to the Clavien classification

Proportion of patients experiencing at least one postoperative complication, classified according to Clavien-Dindo, in malnourished patients with versus without nutritional support.

Time frame
Day 30

Secondary outcomes

Other outcomes

Sponsors and contacts

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University Hospital, Bordeaux

Lead sponsor

French Eso-Gastric Tumors Working Group

Collaborator