Evaluation of the Benefit of Exercise Testing for the Diagnosis of Obstruction in the Coronary Arteries of the Heart

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Sud Francilien

About this trial

The purpose of this study is to determine whether exercise testing can detect an obstruction in a coronary artery, and, thereby, can avoid performing a coronary imaging in some cases.

Patients with a suspicion of coronary artery disease perform an exercise test on an exercise bike with increasing load. EKG, blood pressure, and other parameters are monitored. Patients benefit also of either a cardiac CT scan or a coronary angiography to establish whether they really have coronary obstruction.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Starting betweew 1/1/2019 and 3/1/2022

18 year-old patients or older

Patients with both exercise testing and either Cardiac CT or coronary angiography within 3 months

Patients informed and not opposing to their participation to the study

Disqualifiers

Patients unable to fully understand the information related to the study

Trial population

Out-patients attending Centre Hospitalier Sud Francilien's cardiology department.

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

  • Exercise test

    Diagnostic test

    exercise test on an exercise bike with increasing load

  • Cardiac CT

    Diagnostic test

    cardiac CT scan

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Area Under the ROC curve

AUC of the ROC curve defined by DP increase and significant coronary artery stenosis or not

Time frame
at 3 months

Secondary outcomes

1

Youden threshold

Maximalization of the difference between sensitivity and 1-specificity

Time frame
at 3 months
2

ROC for women

AUC for women

Time frame
at 3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.