About this trial
The purpose of this study is to determine whether exercise testing can detect an obstruction in a coronary artery, and, thereby, can avoid performing a coronary imaging in some cases.
Patients with a suspicion of coronary artery disease perform an exercise test on an exercise bike with increasing load. EKG, blood pressure, and other parameters are monitored. Patients benefit also of either a cardiac CT scan or a coronary angiography to establish whether they really have coronary obstruction.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Starting betweew 1/1/2019 and 3/1/2022
18 year-old patients or older
Patients with both exercise testing and either Cardiac CT or coronary angiography within 3 months
Patients informed and not opposing to their participation to the study
Disqualifiers
Patients unable to fully understand the information related to the study
Trial population
Out-patients attending Centre Hospitalier Sud Francilien's cardiology department.
Trial design
Cohort
Other
Treatments tested in this trial
Exercise test
Diagnostic testexercise test on an exercise bike with increasing load
Cardiac CT
Diagnostic testcardiac CT scan
Treatment groups
Trial outcomes
Primary outcomes
Area Under the ROC curve
AUC of the ROC curve defined by DP increase and significant coronary artery stenosis or not
Secondary outcomes
Youden threshold
Maximalization of the difference between sensitivity and 1-specificity
ROC for women
AUC for women
Sponsors and contacts
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