Evaluation of the Elasticity of the Mitral Valve

ConditionMitral Valve Disease

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age45+

SponsorCentre Hospitalier Universitaire de Saint Etienne

About this trial

There is no information in the literature on the mechanobiological characteristics of mitral valve chords in living humans. All examinations were carried out on tissues taken from animals, either from cadavers or from frozen human tissues. The objective is to determine mechanobiological and histological characteristics of the mitral valve chords in living humans, as well as to compare differences in elasticity in different groups (Group A: patients with mitral valve prolapse versus Group B: patients with restrictive ischemic mitral valve).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patients with mitral calcification

Mitral valve rheumatic disease

Mitral valve infections

Redo surgery on the mitral valve

Trial population

Patients programmed for mitral valve replacement who have more than 45 years old

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Data collection on patient history and intraoperative results.
Other intervention
Data collection on patient history and intraoperative results.

Treatment groups

30 Participants

are divided into 2 treatment groups

Group A: Mitral valve prolapse1 intervention

Group B: Restrictive ischemic mitral valve1 intervention

Trial outcomes

Primary outcomes

Maximum value of Young's modulus

Comparison of elasticity difference between the two groups

Time frame

Hour 1

Secondary outcomes

First histological evaluation

Determine the histological characteristics of living humans

Time frame

Hour 1

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Centre Hospitalier Universitaire de Saint Etienne

Lead sponsor

Source ClinicalTrials.gov

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