The aim of this study is to assess the impact of implementing a patient education and preparation protocol for FDG PET (18F-FDG PET) imaging on the quality of imaging results.
18F-FDG (18Fluor-FluoroDesoxyGlucose) PET (Positron Emission Tomography) is indicated for the diagnosis of cardiac inflammation. To detect cardiac inflammation, the myocardium (heart muscle) must be prevented from absorbing glucose from the diet (FDG). To achieve this, patient preparation is essential. Poor preparation can compromise the interpretation of results, causing diagnostic delay.
To answer the research question, the investigators plan to include 138 people with suspected infective endocarditis or cardiac sarcoidosis, in two institutions of the Assistance Publique - Hôpitaux de Paris: Hôpital Européen Georges Pompidou and Hôpital Cochin-Port-Royal, located respectively at 20 rue Leblanc 75015 Paris and 27 rue du Faubourg Saint-Jacques 75014 Paris.
Presence of a prescription validated by the nuclear medicine department for an 18F-FDG PET scan for the detection of inflammation of cardiac inflammation or infection
Age greater than or equal to 18
Membership of a social security scheme or equivalent
Patients with an e-mail address
Pregnancy or breast-feeding
Patients (inpatients or outpatients) already on a diet (including ketogenic)
Patients who do not understand protocol
Patients deprived of liberty by judicial or administrative decision
Parallel
Sending a link to the video
Other interventionSending a link to the educational video (3 min, 34 sec.) prepared as part of the study, explaining the importance of proper preparation and the diet to follow.
Compliance questionnaire
BehavioralPatient completes a questionnaire on compliance with preparation instructions on the day of the imaging test.
Determination of beta-hydroxybutyrate (BHB) in capillary blood
Biological/VaccineDetermination of beta-hydroxybutyrate (BHB) in capillary blood prior to imaging examination.
Evaluate the benefit of implementing a patient education protocol prior to myocardial 18F-FDG PET on the removal of residual myocardial fixation compared to the usual procedure of sending instructions.
Interpretation of imaging results : Success rate of suppression of residual myocardial FDG uptake. Success criteria according to 4 grades. Grade 1 (no residual FDG uptake), grade 2 (moderate FDG uptake in basal LV segments), grade 3 (residual FDG fixation interfering with interpretation) or grade 4 (diffuse, intense FDG uptake). Grades 1 and 2 define success. Centralized review by two independent nuclear medicine physicians and definition of residual FDG uptake in the myocardium blinded to the inclusion group. If there was a discrepancy between the scores, rereading by a 3rd nuclear physician.
Evaluate the value of determining ketone bodies in capillary blood prior to the 18F-FDG PET indicated for infectious endocarditis or cardiac sarcoidosis to predict its success
Measurement of ketone bodies (BHB) on a capillary blood sample just before the imaging.
Evaluate whether the patient education protocol leads to greater compliance with dietary instructions prior to 18F-FDG PET.
Use of a questionnaire prepared and distributed by radio operators to the patient on arrival on the day of the imaging.
Investigate whether certain drug excipients are likely to influence PET-18F-FDG results
Collection of medications taken by the patient in the 24 hours preceding the imaging.
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