Evaluation Of The Relationship Between The Conut Score And Balance And Functional Status In Patients With Chronic Stroke

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorMarmara University

About this trial

The primary aim of this study is to evaluate the relationship between the CONUT score, which reflects nutritional status, and balance performance in patients with chronic stroke. The secondary aims are to investigate the association between the CONUT score and functional status and stroke-specific quality of life, as well as to assess the relationships of mid-upper arm circumference, an anthropometric indicator of nutritional status, and ultrasonographic rectus femoris muscle thickness, which reflects muscle mass, with balance performance, functional status, and stroke-specific quality of life. In addition, the study aims to examine the relationships between bone mineral density and balance, functional status, and ambulation level in patients with chronic stroke.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Being 18 years of age or older

Having a diagnosis of ischemic or hemorrhagic stroke

At least 6 months having elapsed since the stroke event (chronic phase)

Being clinically stable

Disqualifiers

Acute or subacute stroke phase (< 6 months)

Inability to administer assessment scales due to severe cognitive impairment or aphasia

Presence of other neurological disorders that may significantly affect balance and functional status (e.g., Parkinson's disease, multiple sclerosis, peripheral neuropathy)

Significant orthopedic conditions unrelated to stroke (e.g., advanced hip or knee osteoarthritis, lower extremity amputation)

Trial population

A total of 47 patients with chronic stroke, aged between 18 and 85 years, who were followed in the Physical Medicine and Rehabilitation and Neurology outpatient clinics of Marmara University Pendik Training and Research Hospital and met the study inclusion criteria.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

47 Participants
are grouped into 1 trial group
Group A: Patients with chronic stroke

Trial outcomes

Primary outcomes

1

Berg Balance Scale

The Berg Balance Scale is a measure developed to assess individuals' balance performance and consists of 14 items that include activities of daily living. Each item is scored between 0 and 4, with the total score ranging from 0 to 56. Lower scores indicate poorer balance performance and an increased risk of falls.

Time frame
At baseline

Secondary outcomes

1

Tinetti Performance-Oriented Mobility Assessment

This measure was developed to evaluate individuals' balance and gait performance and consists of balance and gait subscales. The balance subscale is scored between 0 and 16, while the gait subscale is scored between 0 and 12, resulting in a total score ranging from 0 to 28. Lower scores indicate a higher risk of falls and poorer mobility.

Time frame
At baseline
2

Stroke-Specific Quality of Life Scale (SS-QOL)

The Stroke-Specific Quality of Life Scale is a multidimensional measure developed to evaluate stroke-specific quality of life, encompassing physical, functional, and psychosocial domains in patients with stroke. The scale consists of a total of 49 items, each scored on a scale from 1 to 5, with higher total scores indicating a better quality of life.

Time frame
At baseline

Other outcomes

1

Controlling Nutritional Status (CONUT) Score

The CONUT score is a laboratory-based screening index developed to assess patients' nutritional status. It is calculated using serum albumin level, total lymphocyte count, and total cholesterol concentration. Scoring is based on the combined evaluation of these three parameters, and the total score ranges from 0 to 12; higher scores indicate an increased risk of malnutrition and greater severity of nutritional impairment.

Time frame
At baseline
2

Mid-Upper Arm Circumference (MUAC)

It is a simple anthropometric method that indirectly assesses an individual's muscle and adipose tissue and is commonly used to evaluate nutritional status and the risk of malnutrition. The measurement is typically performed at the midpoint between the acromion and the olecranon using a flexible measuring tape and recorded in centimeters. The obtained values are interpreted by comparison with age- and sex-specific reference values. In our study, mid-upper arm circumference measurements will be obtained from both the hemiplegic and non-affected sides of the patients and evaluated comparatively.

Time frame
At baseline
3

Rectus Femoris Muscle Thickness

Rectus femoris muscle thickness is a parameter used in the assessment of muscle mass and sarcopenia and can be measured non-invasively using ultrasonography. The measurement is typically performed by placing the ultrasound probe at the midpoint between the anterior superior iliac spine and the superior border of the patella, and measuring the muscle thickness between the fascial boundaries in millimeters or centimeters. There is no standardized scoring system for this measurement; the obtained values are generally reported as absolute muscle thickness or interpreted by comparison with the contralateral side, population reference values, or clinical parameters. In our study, rectus femoris muscle thickness will be

Time frame
The baseline
4

Bone Mineral Densitometry (BMD)

Bone mineral densitometry is an imaging method used to assess bone mineral density and is most commonly measured using dual-energy X-ray absorptiometry (DXA). Measurements are typically obtained from the lumbar spine and femoral neck regions, and bone mineral density is reported in g/cm². Evaluation is performed using the T-score and Z-score. A T-score ≥ -1 is considered normal, a T-score between -1 and -2.5 indicates osteopenia, and a T-score ≤ -2.5 is classified as osteoporosis.

Time frame
At baseline

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