About this trial
ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants.
In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure.
The aim of the study is to assess the patient's outcome
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Out-of-hospital cardiac arrest
enrolled in the ECPR program
18 years old or more
Low-flow estimated <60minutes
Disqualifiers
traumatic cardiac arrest
major comorbidities
Trial population
All patients presenting with refractory out-of-hospital cardiac arrest and enrolled in the ECPR program in Nancy, France. Inclusion criteria for the ECPR program are the following: * Age: 18-65 years * No major comorbidity * Witnessed non traumatic cardiac arrest * Low-flow to ECPR estimated of less than 60 minutes
Trial design
Case-only
Retrospective
Treatments tested in this trial
ECPR for out-of-hospital cardiac arrest
Other interventionPatient with out-of-hospital cardiac arrest enrolled in the ECPR protocol
Treatment groups
Trial outcomes
Primary outcomes
Survival
Survival rate of patients enrolled in the protocol
Secondary outcomes
Delays
Delay between cardiac arrest and ECPR implementation
Neurological outcome
Evaluation of neurological outcome of survivors after cardiac arrest using the Rankin score
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: