About this trial
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:
• How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Older than 18 years
Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.
Able to provide oral and written informed consent
Able to read and speak Danish
Disqualifiers
Prior colorectal cancer diagnosis
History of stenosis of the gastrointestinal tract
Previous treatment of inflammatory bowel disease
Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)
Trial population
Patients admitted to Odense University Hospital with anaerobic blood stream infection. Patients who are discharged before result of blood culture with anaerobic gut-associated bacteria, will be contacted by letter and offered participation in the study.
Trial design
Cohort
Cross-sectional
Treatments tested in this trial
Colon capsule endoscopy
Diagnostic testPillCam Colon 2
Treatment groups
Trial outcomes
Primary outcomes
Colorectal cancer and precancerous tumors
Prevalence of colorectal cancer and precancerous tumors using colon capsule endoscopy
Sponsors and contacts
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