Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorOdense University Hospital

About this trial

The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:

• How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Older than 18 years

Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.

Able to provide oral and written informed consent

Able to read and speak Danish

Disqualifiers

Prior colorectal cancer diagnosis

History of stenosis of the gastrointestinal tract

Previous treatment of inflammatory bowel disease

Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)

Trial population

Patients admitted to Odense University Hospital with anaerobic blood stream infection. Patients who are discharged before result of blood culture with anaerobic gut-associated bacteria, will be contacted by letter and offered participation in the study.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

  • Colon capsule endoscopy

    Diagnostic test

    PillCam Colon 2

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Colorectal cancer and precancerous tumors

Prevalence of colorectal cancer and precancerous tumors using colon capsule endoscopy

Time frame
4-8 weeks after hospitalization with anaerobic gut-associated bacteria

Secondary outcomes

Other outcomes

Sponsors and contacts

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