Exercise Capacity, Muscle Oxygenation, and Physical Activity Between Patients With Interstitial Lung Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorGazi University

About this trial

Interstitial lung diseases (ILD) are a group of chronic respiratory diseases that cause significant mortality and morbidity worldwide. Although there are studies in the literature comparing different lung disease groups with healthy individuals, it has been determined that there is no study comparing the exercise capacity, muscle oxygenation, physical activity level, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, quality of life and sleep quality of individuals diagnosed with ILD with healthy individuals.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients diagnosed with ILD according to ATS/ERS criteria,

Ages between 18 and 75,

Pulmonary infection during the previous month,

Participants who voluntarily participated in the study were included.

Disqualifiers

Acute pulmonary exacerbation or respiratory infection in the last four weeks

Obstructive lung disease

Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions

Recent participation in a planned exercise program (within three months)

Trial population

Patients diagnosed with ILDs and healthy individuals

Trial design

Design model

Case-control

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

40 Participants
are grouped into 2 trial groups
Group A: Patients with ILD
Group B: Healthy Controls

Trial outcomes

Primary outcomes

1

Maximal exercise capacity

Maximal exercise capacity will be assessed by symptom-limited cardiopulmonary exercise testing on a treadmill at gradually increasing workload, and oxygen consumption will be measured during the test.

Time frame
Trough study completion, an average of 1 year
2

Muscle Oxygenation

Muscle oxygenation before, during and after exercise tests will be measured with a near-infrared spectroscopy device.

Time frame
Trough study completion, an average of 1 year
3

Physical Activity Level

Individuals' physical activity level will be assessed with a multi-sensor physical activity monitor.

Time frame
Trough study completion, an average of 1 year

Secondary outcomes

1

Upper extremity functional exercise capacity

To evaluate upper extremity functional exercise capacity, 6-minute pegboard and ring tests will be applied twice with 15-30 minute intervals. Before the test, individuals will be seated and rested for at least 10 minutes. Individuals will be provided with detailed information about the application of the test before the test. Patients will be informed not to interfere with rings that fall during the test and to continue the test. It will be explained that they can stop and rest if they feel too uncomfortable to continue the test, but this time will be included in the test duration. Before the actual test, subjects will be allowed to move up and down one loop as a practice to learn the test procedure. As a test result, the total number of rings worn at the end of six minutes will be recorded in numbers.

Time frame
Trough study completion, an average of 1 year
2

Lower extremity functional exercise capacity

A 6-minute walking test will be applied according to ATS/ERS criteria to evaluate lower extremity functional exercise capacity.

Time frame
Trough study completion, an average of 1 year
3

Dyspnea

The assessment of dyspnea at rest, during, and after exercise training will be made with the Modified Borg scale. The Modified Borg scale is a subjective scale and scores the shortness of breath at rest and/or during activity between 0-10. The lowest score of 0 (zero) indicates 'none', and the highest score of 10 (ten) indicates 'maximal' shortness of breath. The Modified Medical Research Council (MMRC) dyspnea scale will be used to determine the perception of dyspnea during activities of daily living. The London Chest Activities of Daily Living Scale, developed by Garrod et al. to examine dyspnea that occurs with daily living activities in chronic obstructive pulmonary disease and whose Turkish validity and reliability were performed by Saka et al., will be used to assess shortness of breath that occurs during activities of daily living.

Time frame
Trough study completion, an average of 1 year
4

Respiratory Muscle Strength

Maximal inspiratory and expiratory muscle strength will be evaluated using mouth pressure device.

Time frame
Trough study completion, an average of 1 year

Other outcomes

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