About this trial
Interstitial lung diseases (ILD) are a group of chronic respiratory diseases that cause significant mortality and morbidity worldwide. Although there are studies in the literature comparing different lung disease groups with healthy individuals, it has been determined that there is no study comparing the exercise capacity, muscle oxygenation, physical activity level, respiratory functions, respiratory and peripheral muscle strength, inspiratory muscle endurance, quality of life and sleep quality of individuals diagnosed with ILD with healthy individuals.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients diagnosed with ILD according to ATS/ERS criteria,
Ages between 18 and 75,
Pulmonary infection during the previous month,
Participants who voluntarily participated in the study were included.
Disqualifiers
Acute pulmonary exacerbation or respiratory infection in the last four weeks
Obstructive lung disease
Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions
Recent participation in a planned exercise program (within three months)
Trial population
Patients diagnosed with ILDs and healthy individuals
Trial design
Case-control
Retrospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Maximal exercise capacity
Maximal exercise capacity will be assessed by symptom-limited cardiopulmonary exercise testing on a treadmill at gradually increasing workload, and oxygen consumption will be measured during the test.
Muscle Oxygenation
Muscle oxygenation before, during and after exercise tests will be measured with a near-infrared spectroscopy device.
Physical Activity Level
Individuals' physical activity level will be assessed with a multi-sensor physical activity monitor.
Secondary outcomes
Upper extremity functional exercise capacity
To evaluate upper extremity functional exercise capacity, 6-minute pegboard and ring tests will be applied twice with 15-30 minute intervals. Before the test, individuals will be seated and rested for at least 10 minutes. Individuals will be provided with detailed information about the application of the test before the test. Patients will be informed not to interfere with rings that fall during the test and to continue the test. It will be explained that they can stop and rest if they feel too uncomfortable to continue the test, but this time will be included in the test duration. Before the actual test, subjects will be allowed to move up and down one loop as a practice to learn the test procedure. As a test result, the total number of rings worn at the end of six minutes will be recorded in numbers.
Lower extremity functional exercise capacity
A 6-minute walking test will be applied according to ATS/ERS criteria to evaluate lower extremity functional exercise capacity.
Dyspnea
The assessment of dyspnea at rest, during, and after exercise training will be made with the Modified Borg scale. The Modified Borg scale is a subjective scale and scores the shortness of breath at rest and/or during activity between 0-10. The lowest score of 0 (zero) indicates 'none', and the highest score of 10 (ten) indicates 'maximal' shortness of breath. The Modified Medical Research Council (MMRC) dyspnea scale will be used to determine the perception of dyspnea during activities of daily living. The London Chest Activities of Daily Living Scale, developed by Garrod et al. to examine dyspnea that occurs with daily living activities in chronic obstructive pulmonary disease and whose Turkish validity and reliability were performed by Saka et al., will be used to assess shortness of breath that occurs during activities of daily living.
Respiratory Muscle Strength
Maximal inspiratory and expiratory muscle strength will be evaluated using mouth pressure device.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.