EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

ConditionCancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-89
SponsorAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

About this trial

This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 20-89 years

Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study.

Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI

Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.

Disqualifiers

None

Trial population

Individuals diagnosed with cancer on an exercise program at the AHN Exercise Oncology and Resiliency Center

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Dose escalated resistance training

    Other intervention

    All individuals will be engaging in resistance training during and/or after their cancer treatment

Treatment groups

100 Participants
are divided into 5 treatment groups
Group A: General cancer patients1 intervention
Group B: Head and neck cancer patients1 intervention
Group C: Colorectal cancer patients1 intervention
Group D: Pancreatic cancer patients1 intervention
Group E: Metastatic breast cancer patients1 intervention

Trial outcomes

Primary outcomes

1

Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis

Measurement on bioimpedance analysis machine (Inbody 970)

Time frame
3 months
2

Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound

Measurement via ultrasound and calculation with Jackson-Pollack calculations

Time frame
3 months
3

Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen

Measurement on bioimpedance analysis machine (Inbody 970)

Time frame
3 months

Secondary outcomes

1

Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen

Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen

Time frame
3 months
2

Determine changes in Y-balance score for each leg

Y-balance score adds up the distance each leg can move in the front and side directions, divided by the length of the hip. This correlates inversely with fall risk.

Time frame
3 months
3

Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen

Load is calculated by multiplying sets by repetitions by weight lifted for a specific exercise

Time frame
3 months
4

Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen

EQ-5D asks 5 questions rates from 1-5 and an overall rating of health

Time frame
3 months

Other outcomes

Sponsors and contacts

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