About this trial
Physical exercise is an important supportive therapy for cancer patients, as it improves quality of life in general and might mitigate the side effects of drug treatment. For patients with multiple myeloma in particular, significantly less evidence on the effectiveness of exercise therapy is available due to the fact that this disease is associated with severe bone degradation which might affect bone stability. Advances in oncologic drug treatment have improved overall survival in multiple myeloma significantly. Therefore, there is an increased interest for recommendations on physical activity in this patient group. Due to uncertainties regarding safety and feasibility of exercise therapy in multiple myeloma, both patients and therapists often remain hesitant. Therefore, an orthopaedic outpatient clinic has been established at the Myeloma Center of Heidelberg University Hospital. Here, patients receive consultation on bone stability and individualized physical exercise plans. Based on the expertise gained at the orthopaedic outpatient clinic, the aim of this study is to establish and evaluate structural measures for improved rehabilitation in multiple myeloma and to integrate them into routine clinical care.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
newly diagnosed multiple myeloma
Survival prognosis > 6 months
ECOG status ≤ 3
Age ≥18 years
Disqualifiers
physical or mental limitation that would prevent participation in the training program or the planned follow-up visits
Trial design
Single group
Treatments tested in this trial
Orthopedic consultation and rehabilitation by excercise therapy
Other interventionAll patients will receive a continuous orthopaedic consultation on bone stability and recommendations for exercise therapy during the different phases of systemic myeloma therapy. Thereby, structural measures to improve rehabilitation in multiple myeloma will be established and evaluated with the intention of integrating them into routine clinical care.
Treatment groups
Trial outcomes
Primary outcomes
Change in physical function
Results of the EORTC QLQ-C30 questionnaire ("Physical functioning" scale)
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: