Exercise Therapy for Multiple Myeloma Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity Hospital Heidelberg

About this trial

Physical exercise is an important supportive therapy for cancer patients, as it improves quality of life in general and might mitigate the side effects of drug treatment. For patients with multiple myeloma in particular, significantly less evidence on the effectiveness of exercise therapy is available due to the fact that this disease is associated with severe bone degradation which might affect bone stability. Advances in oncologic drug treatment have improved overall survival in multiple myeloma significantly. Therefore, there is an increased interest for recommendations on physical activity in this patient group. Due to uncertainties regarding safety and feasibility of exercise therapy in multiple myeloma, both patients and therapists often remain hesitant. Therefore, an orthopaedic outpatient clinic has been established at the Myeloma Center of Heidelberg University Hospital. Here, patients receive consultation on bone stability and individualized physical exercise plans. Based on the expertise gained at the orthopaedic outpatient clinic, the aim of this study is to establish and evaluate structural measures for improved rehabilitation in multiple myeloma and to integrate them into routine clinical care.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

newly diagnosed multiple myeloma

Survival prognosis > 6 months

ECOG status ≤ 3

Age ≥18 years

Disqualifiers

physical or mental limitation that would prevent participation in the training program or the planned follow-up visits

Trial design

Design model

Single group

Treatments tested in this trial

  • Orthopedic consultation and rehabilitation by excercise therapy

    Other intervention

    All patients will receive a continuous orthopaedic consultation on bone stability and recommendations for exercise therapy during the different phases of systemic myeloma therapy. Thereby, structural measures to improve rehabilitation in multiple myeloma will be established and evaluated with the intention of integrating them into routine clinical care.

Treatment groups

71 Participants
are divided into 1 treatment group
Group A: Orthopedic consultation and exercise to evaluate structural measures and improve rehabilitationActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Change in physical function

Results of the EORTC QLQ-C30 questionnaire ("Physical functioning" scale)

Time frame
From enrollment to the end of induction therapy after 18 weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: