Exercise to Slow Cardiovascular Ageing Progression
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21-100
SponsorNational Heart Centre Singapore
About this trial
In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age >=21 years old
Outdoor ambulant
Disqualifiers
Wheelchair or bed-bound
Dementia
Residing in sheltered or nursing home
Cancer
Trial population
Recruited through research studies and community studies.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
450 Participants
are grouped into 4 trial groupsGroup A: A
Group B: B
Group C: C
Group D: D
Trial outcomes
Primary outcomes
1
Metabolite profiles
To measure changes in serum metabolite levels among participants pre and post exercise intervention.
Time frame
12 Months2
Cardiovascular structure and function
To measure changes in CV structure and function (diastolic function, arterial stiffness) among participants.
Time frame
12 MonthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov