Exercise Training and Vitamin D Metabolism

ConditionsObesity & Overweight Vitamin D

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age35-50

SponsorUniversity of Thessaly

About this trial

The prevalence of Vitamin D deficiency is significantly higher in adults with overweight/obesity compared to those with normal body mass index (BMI). The "entrapment" of Vitamin D in adipose tissue due to impaired lipolytic stimulation and/or adipose tissue dysfunction has been proposed as the driving mechanism. Exercise training has been proposed as a promising strategy to increase mobilization of Vitamin D from adipose tissue, given its well described role in stimulating lipolysis. Indeed, a recent study revealed that participation in moderate-intensity cardiovascular type exercise over winter can mitigate the decline in 25-hydroxyvitamin D \[25(OH)D\] in adults with overweight/obesity, independent of weight loss. The aim of this study is to investigate the impact of hybrid-type high-intensity interval training over winter on vitamin D metabolism, in adults with overweight/obesity.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

BMI = 25-35 kg/m2

Absence of musculoskeletal injuries

Absence of chronic health-related complications

Non-smokers

Disqualifiers

Consumption of Vitamin D supplements

Consumption of anti-inflammatory drugs, statins and/or steroids

Trial design

Design model

Parallel

Treatments tested in this trial

Exercise training
Other intervention
Receive a balanced diet and participate in three hybrid-type high-intensity interval training sessions per week over a 12-week period
Control
Other intervention
Receive a balanced diet but abstain from any type of exercise training

Treatment groups

30 Participants

are divided into 2 treatment groups

Group A: Exercise groupExperimental treatment 1 intervention

Group B: Control groupActive comparator 1 intervention

Trial outcomes