Explore the Effect of Bitter Melon Peptides on Glycemic Control and Metabolic Indicators in Diabetic Patients

ConditionDiabetes
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-80
SponsorChanghua Christian Hospital

About this trial

The goal of this clinical trial is to learn the potential of bitter melon peptides in stabilizing blood glucose in diabetic adults. It will also learn about the effects of bitter melon peptides on metabolic parameters. The main questions it aims to answer are:

* the regulatory effects of bitter melon peptides on glycemic variability * impact on glycemic and metabolic indicators Researchers will compare bitter melon peptides to a placebo (a look-alike capsule that contains Microcrystalline Cellulose) to see if bitter melon peptides works to stabilizing blood glucose.

Participants will:

* Take bitter melon peptides or a placebo every day for 12 weeks * Visit the clinic on day 0, day 7, day 28 and day 84 for checkups and tests * Glucose levels were monitored continuously by CGMs in the first 7 days and fasting blood samples were drawn at first visit (day0), third visit (day 28) and fourth visits (day 84)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • bitter melon peptides

    Dietary supplement

    Momordica charantia extract

Treatment groups

160 Participants
are divided into 2 treatment groups
Group A: bitter melon peptidesExperimental treatment 1 intervention
Group B: Placebo groupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

glycemic variability

mean amplitude of glucose excursions and coefficient of variation, using CGM

Time frame
From enrollment (day0) to day7

Secondary outcomes

1

glycemic control

Glycated hemoglobulin A1C

Time frame
From enrollment (day0) to the end (day84)

Other outcomes

1

metabolic indicator

C-peptide

Time frame
From enrollment (day0) to the end (day84)

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Changhua Christian Hospital

Lead sponsor

China Medical University, Taiwan

Collaborator

This trial is not recruiting at the moment. You can still explore other options: