About this trial
This is the prospective, observational cohort study (Radiogenomics-Urinary), which aims to explore the relationship between the imaging information of urologic cancer patients, tumor microenvironment and the prognosis of urologic cancer patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients treated for urologic cancer in Wuhan Union Hospital from August 2024 to August 2027;
Aged > 18 years old;
At least one CT scan or MRI scan before treatment;
Tissue biopsy pathological examination confirmed the diagnosis of the above tumors.
Disqualifiers
Poor image quality;
Incomplete clinical data or loss of follow-up;
Presence of another primary malignancy other than urologic cancer;
Unclear pathological diagnosis。
Trial population
Patients treated for urologic cancer
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Correlation analysis of sequencing results and body composition
Conducting correlation analysis between body composition and results of multi-omics sequencing.
Correlation analysis of sequencing results and tumor radiomic features
Conducting correlation analysis between radiomic features and results of multi-omics sequencing.
Secondary outcomes
Constructing tumor microenvironment prediction model
Constructing radiomic model to predict tumor microenvironment. The indicator is the area under the curve (AUC) of the prediction model
Constructing a multi-dimensional prognostic prediction model
A high-dimensional model was constructed to predict the prognosis of patients through multi-omics sequencing data, body composition, and tumor radiomic features. The indicator is the area under the curve (AUC) of the prediction model.
Sponsors and contacts
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