About this trial
To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Participants diagnosed with chronic (≥90 days duration) CIPN (due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds or ionizing irradiation) of the lower extremity, seen at Pain Management Center at MD Anderson Cancer Center
Participants reports baseline pain ≥ 4 (0-10 scale, NRS)
Participants between ages 18-85 years old
Participants who have completed chemotherapy within the previous year at the time of enrollment
Disqualifiers
Participants with cognitive dysfunction
Participants with recent history (<6 months) of drug or alcohol abuse
Participants with open skin lesion or undergoing antibiotic therapy for local for systemic infection
Participants with allergies to local anesthesia, steroids, or adhesives
Trial design
Single group
Treatments tested in this trial
Peripheral Nerve Stimulation
Other interventionThe leads are inserted through a needle. If needed, the study team may give participants anesthetic (for example, as a cream/gel on your skin and/or as an injection) to numb the area where the leads will be injected.
Treatment groups
Trial outcomes
Primary outcomes
Safety and adverse events (AEs)
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0
Sponsors and contacts
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