The purpose of this randomized control trial is to compare how food cravings, food selection, and food consumption change in response to frequent food advertisements compared to non-food advertisements in adults taking GLP-1 (weight loss) medications. The primary question we aim to answer is: do GLP-1 medications reduce an individual's vulnerability to external triggers that drive food cravings and consumption?
Participants will:
* report daily food consumption for a total of 10 days, * receive eight daily prompts to view food or non-food related advertisements, and respond to a short 9-question survey for 7 days, * answer several questionnaires, * and complete two in-person visits to complete a virtual reality food selection task.
Adults (18+) with overweight or obesity (BMI >25 kg/m2)
On an injectable form of tirzepatide GLP-1 medication at a minimum dose of 7.5 mg, taking it as prescribed by their doctor
Not currently taking an incretin-based medication at baseline other than the GLP-1 medication
Fluent in English
Do not have consistent access to a smart phone that can access the study software
Diagnosed with cognitive or physical disability or epilepsy
Adults taking a compound GLP-1
Parallel
Food advertisements
BehavioralVideos and images of food and beverage advertisements from popular brands and/or restaurants
Tech advertisements
BehavioralVideo and photo advertisements of popular tech tools
Mean food cue reactivity scores in the afternoon
Average scores of craving levels for each group following afternoon advertisement viewing sessions
Mean food cue reactivity scores in the morning
Average scores of craving levels for each group following morning advertisement viewing sessions
Mean food cue reactivity scores in the evening
Average scores of craving levels for each group following evening advertisement viewing sessions
Mean food cue reactivity scores overall
Average scores of craving levels for each group over all viewing sessions
Change from baseline in energy density of foods selected in the virtual buffet
Changes in food noise since being on medication questionnaire
Questionnaire assessing various aspects of food noise at present compared to before the medication
Changes in reasons for purchasing foods questionnaire
A questionnaire that assesses how five factors impact purchasing choices, and how the main factors have changed between prior to starting the medication and after.
Individual Food Cue Responsiveness--Trait
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Penn State University
Lead sponsor
Penn State Health
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
