Health TrialsbyHealthPanel

Exploring the Links Between Hearing, Cognition and Brain Activity in People With Tinnitus

ConditionTinnitus
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitut Pasteur

About this trial

The goal of this observational study is to understand the mechanisms underlying tinnitus, and improve the clinical assessment strategies needed to develop targeted therapeutic interventions by comparing endogenous attention capacities in healthy subjects and subjects with tinnitus

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age ≥ 18 years

Good written and oral comprehension of the French language

Normal or corrected vision

Disqualifiers

Presence of a known neurological disorder

Presence of a known degenerative pathology

Presence of a known hearing impairment

Presence of a motor disability of the upper limbs

Trial design

Design model

Parallel

Treatments tested in this trial

  • Quality of Life questionnaires

    Other intervention

    Subjects will complete a number of self-questionnaires on subjects such as attention span, anxiety levels and sleep quality.

  • Hearing tests

    Other intervention

    listening to sounds on headphones and repeating words

  • Auditory prediction task

    Behavioral

    listening to sounds and assessing auditory perception

  • Attention task

    Behavioral

    assessment of reaction time to visual or auditory cues

Treatment groups

114 Participants
are divided into 2 treatment groups
Group A: Healthy subjectsSham comparator 4 interventions
Group B: Subjets with tinnitusExperimental treatment 4 interventions

Trial outcomes

Primary outcomes

1

Contingent negative variation (CNV) in EEG

Time frame
2 hours

Secondary outcomes

1

Response reaction time (in ms)

Comparison of reaction time (RT) variability following response button presses in behavioural tasks

Time frame
2 hours
2

Answer accuracy (% correct answers)

Comparison of the variability of the number of correct responses following button presses in behavioural tasks.

Time frame
2 hours
3

Cerebral oscillations (alpha bands) obtained by EEG during behavioural tasks

Time frame
2 hours
4

Skin conductance (μS)

during behavioral task

Time frame
2 hours

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Institut Pasteur

Lead sponsor

IHU reConnect

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: