Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age60+
SponsorBeijing Chao Yang Hospital

About this trial

To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Written informed consent

undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia

ASA grade: II-IV

older than 60 years

Disqualifiers

history of severe neurological diseases and psychiatric diseases

history of drug abuse

severe hearing or vision impairment

preoperative delirium

Trial population

1. older than 60 years 2. ASA grade: I-III 3. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 4. able to complete cognitive function tests

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • cardiovascular surgery

    Procedure/Surgery

    Heart bypass surgery; Heart valve replacement surgery

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: Perioperative Neurocognitive Disorders1 intervention
Group B: No-Perioperative Neurocognitive Disorders1 intervention

Trial outcomes

Primary outcomes

1

The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery

Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using The Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Time frame
2025.08

Secondary outcomes

1

The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery

Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) .

Time frame
2025.08
2

Electroencephalography features in patients with postoperative delirium

Electroencephalography was collected in delirium patients one week(7±2 days) after surgery. Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with postoperative delirium will be included in the analysis.

Time frame
2025.08

Other outcomes

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