About this trial
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Written informed consent
undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia
ASA grade: II-IV
older than 60 years
Disqualifiers
history of severe neurological diseases and psychiatric diseases
history of drug abuse
severe hearing or vision impairment
preoperative delirium
Trial population
1. older than 60 years 2. ASA grade: I-III 3. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 4. able to complete cognitive function tests
Trial design
Other
Prospective
Treatments tested in this trial
cardiovascular surgery
Procedure/SurgeryHeart bypass surgery; Heart valve replacement surgery
Treatment groups
Trial outcomes
Primary outcomes
The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery
Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using The Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).
Secondary outcomes
The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery
Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) .
Electroencephalography features in patients with postoperative delirium
Electroencephalography was collected in delirium patients one week(7±2 days) after surgery. Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with postoperative delirium will be included in the analysis.
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