Eye Movement Intervention With Different Memory Reactivation Procedures for Intrusive Traumatic Memories
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorShaanxi Normal University
About this trial
Post-Traumatic Stress Disorder (PTSD) and trauma-related symptoms are often characterized by recurrent intrusive memories that cause distress and interfere with daily functioning. Although trauma-focused interventions such as Eye Movement Desensitization and Reprocessing (EMDR) may be effective, they often involve engagement with trauma-related memories, which can be distressing for some individuals and may affect treatment acceptability. This randomized controlled trial will evaluate a standardized eye-movement-based procedure for trauma-exposed individuals experiencing recurrent intrusive memories. Participants will be randomly assigned to one of several memory-related task conditions involving eye movements. The study will assess the frequency and distress of trauma-related intrusive memories at prespecified assessment points, as well as PTSD symptoms, intervention-related distress, acceptability, and safety. Findings from this trial may help inform the development of tolerable approaches for targeting trauma-related intrusive memories.
Eligibility criteria
Qualifiers
Meet DSM-5 PTSD Criterion A, such as exposure to actual or threatened death, serious injury, or sexual violence; have experienced one or more traumatic events.
Experienced five or more trauma-related intrusive memories during the baseline week.
Have internet access and access to a personal computer suitable for completing the online study tasks.
Have normal or corrected-to-normal vision and be able to complete computerized visual and eye movement tasks.
Disqualifiers
Have fewer than five trauma-related intrusive memories during the baseline week.
Have a current or past psychotic disorder, current manic episode, severe obsessive-compulsive disorder, severe personality disorder, or another severe psychiatric condition judged to interfere with study participation, adherence, or safety.
Have current acute suicidal ideation or behavior, significant risk of harm to self or others, or any condition requiring urgent clinical intervention.
Have current severe substance use disorder or severe substance dependence judged to interfere with study participation or safety.
Trial design
Treatments tested in this trial
- Unconscious Trauma Reactivation plus Eye Movements
- Active Trauma Memory Reactivation plus Eye Movements
- Neutral Memory Reactivation plus Eye Movements
Treatment groups
117 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov