About this trial
Enteral nutrition is the first-line nutritional support method in critically ill patients because it helps preserve gastrointestinal system integrity, reduce the risk of infection, and meet metabolic requirements. However, gastrointestinal motility is frequently impaired in critically ill patients due to physiological stress, hemodynamic instability, sedative and vasopressor medications, mechanical ventilation, and underlying diseases. This may result in enteral feeding intolerance (EFI), which complicates nutritional management.
This prospective observational study aims to determine the demographic, clinical, laboratory, and treatment-related factors associated with enteral feeding intolerance in adult intensive care unit patients and to evaluate the association between enteral feeding intolerance and morbidity and mortality.
Adult patients who are started on enteral nutrition in the Anesthesiology and Reanimation Intensive Care Unit will be prospectively followed. No additional intervention will be performed. Patients will be monitored according to routine intensive care and enteral nutrition protocols. Enteral feeding intolerance and potentially associated factors will be recorded prospectively.
The study is planned to include 102 patients.
Eligibility criteria
Qualifiers
Age ≥18 years
Admission to the Anesthesia Intensive Care Unit
Enteral nutrition planned or initiated during intensive care unit admission
Expected to require enteral nutrition during intensive care unit follow-up
Disqualifiers
Age <18 years
Patients receiving only parenteral nutrition
Patients in whom enteral nutrition is contraindicated throughout the observation period
Patients with insufficient data for evaluation of enteral feeding tolerance
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Locations
Sponsors and collaborators
Eda Cirit Bardakçi
Lead sponsor
Ankara Ataturk Sanatorium Training and Research Hospital
Sponsor institution