Health TrialsbyHealthPanel

Factors Influencing Subjective Visual Quality in Human Eyes

ConditionsCorneal Wavefront AberrationRefractive Errors
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorTianjin Eye Hospital

About this trial

To assess subjective visual symptoms using the QoV questionnaire, measure pupil size using the Atongmu Pupillometer, measure wavefront aberrations using the OPD-Scan III Aberrometer, and measure/calculate the effective optical zone using the Pentacam system. The relationships between pupil size, higher-order aberrations (HOAs), effective optical zone after refractive surgery, and subjective visual symptoms will be explored.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Myopic or myopic astigmatism patients aged 18 to 45 years.

Transparent ocular media, absence of ocular diseases such as corneal leucoma, cataract, etc.

Round pupils with normal light reflex, absence of dyscoria, corectopia, significant persistent pupillary membrane, or absence of the pupil.

Absence of severe psychological or psychiatric disorders, ability to cooperate with examinations and questionnaire completion.

Disqualifiers

Opacities of the ocular media, such as corneal leucoma, cataract, etc.

Pupil deformation, displacement, significant persistent pupillary membrane, or absence of the pupil.

Severe psychological or psychiatric disorders.

Concurrent diagnosis of other ocular diseases (e.g., glaucoma, corneal opacity, uveitis, etc.).

Trial design

Design model

Single group

Treatments tested in this trial

  • Corneal Refractive Surgery

    Procedure/Surgery

    Corneal refractive surgery aims to correct refractive errors by altering the shape of the anterior surface of the cornea or by changing its refractive properties.

Treatment groups

300 Participants
are divided into 1 treatment group
Group A: Corneal refractive surgeryExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Total Higher-Order Aberrations (HOAs)

Root mean square (RMS) of total higher-order aberrations measured using the OPD-Scan III. Units: micrometres (µm)

Time frame
3 months
2

Effective Optical Zone Diameter

Effective optical zone diameter measured using the Pentacam system. Units: millimetres (mm)

Time frame
3 months
3

Central Corneal Thickness

Central corneal thickness measured using the Pentacam system. Units: micrometres (µm)

Time frame
3 months
4

Coma Aberration (RMS)

Coma aberration (root mean square) measured using the OPD-Scan III. Units: micrometres (µm)

Time frame
3 months

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tianjin Eye Hospital

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: