Health TrialsbyHealthPanel

Familial B-cell Lymphoproliferative Disorders

ConditionsLymphoproliferative DisordersPremalignantMonoclonal B-Cell LymphocytosisChronic Lymphocytic Leukemia
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Haifa

About this trial

This study investigates families with at least two cases of B-cell lymphoproliferative disorders (LPD), and evaluates the prevalence of LPD in families, the relationship between medical history, genetic factors, and the risk of familial LPD, and various clinical outcomes for these families in a multiethnic population of Jews and Arabs in Israel.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Pregnant women, special populations and those lacking judgment will not be included

Trial population

Jewish and Arab LPD families with at least 2 family members with LPD.

Trial design

Design model

Family-based

Time perspective

Other

Treatments tested in this trial

  • No intervention

    Other intervention

    No intervention

Treatment groups

1,000 Participants
are divided into 15 treatment groups

15

Treatment groups

See each treatment group below.

Group A: Bnai Zion Medical Center1 intervention
Group B: Tel Aviv Sourasky Medical Center - Ichilov Hospital1 intervention
Group C: Galil Medical Center1 intervention
Group D: Ziv Medical Center1 intervention
Group E: Emek Medical Center1 intervention
Group F: Beilinson Hospital1 intervention
Group G: Meir Medical Center1 intervention
Group H: Kaplan Medical Center1 intervention
Group I: Sheba Medical Center1 intervention
Group J: Rambam Medical Center1 intervention
Group K: Shaare Zdek Medical Center1 intervention
Group L: Hadassah Medical Center1 intervention
Group M: Shamir Medical Center (Assaf Harofeh)1 intervention
Group N: Soroka Medical Center1 intervention
Group O: Assuta Ashdod Hospital1 intervention

Trial outcomes

Primary outcomes

1

Prevalence of familial LPD in Israel

Time frame
5 years
2

Association between medical history and genetic variants and the risk of familial LPD

Time frame
5 years
3

Risk of clinical outcomes among familial LPD and family members

Time frame
15 years

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Haifa

Lead sponsor

Bnai Zion Medical Center

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: