Family Patterns in Resting Metabolic Rate Between Parents and Adult Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorTel Aviv University
About this trial
This study examines whether resting metabolic rate (RMR)-the amount of energy the body uses at rest-is similar between biological parents and their adult children (aged 18 years and older). RMR is the largest component of daily energy expenditure and plays an important role in body weight regulation and overall metabolic health.
Participants from the same family will undergo a single testing session in a metabolic laboratory. RMR will be measured using indirect calorimetry under standardized conditions, along with body composition assessment and basic health information.
The primary goal is to determine whether RMR is correlated within families. The study will also assess whether these similarities remain after accounting for differences in body composition, age, and sex.
This observational study will help improve understanding of how metabolism varies between individuals and the extent to which these differences may be influenced by familial or inherited factors. Findings may contribute to future research on personalized nutrition, obesity risk, and metabolic health.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Biological parent-adult child pairs
Adult children aged ≥18 years
Parents aged 40-60 years
Ability to comply with study procedures, including fasting and resting conditions
Disqualifiers
Current weight loss or active dieting
Known metabolic disorders (e.g., thyroid disease)
Use of medications affecting metabolic rate
Pregnancy
Trial population
Biological parent-adult child families recruited from the general population. Participants are generally healthy adults, including parents aged 40-60 years and their adult children aged 18 years and older, without known metabolic disorders.
Trial design
Design model
Family-based
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
30 Participants
are grouped into 1 trial groupGroup A: Parent-Adult Child Families
Trial outcomes
Primary outcomes
1
Parent-Offspring Correlation in Resting Metabolic Rate
Correlation coefficient (Pearson or Spearman) between resting metabolic rate (RMR) measured in biological parents and their adult children using indirect calorimetry.
Time frame
Single study visit (baseline assessment)Secondary outcomes
1
Adjusted Association Between Parent and Offspring Resting Metabolic Rate
Association between parent and offspring RMR after statistical adjustment for fat-free mass, fat mass, age, and sex.
Time frame
Single study visit (baseline)2
Sex-Specific Parent-Offspring Correlation in Resting Metabolic Rate
Correlation coefficient between parent and offspring RMR stratified by parent-child sex pair.
Time frame
Single study visit (baseline)3
Within-Family Variability in Resting Metabolic Rate
Variability (e.g., standard deviation) of RMR values within families.
Time frame
Single study visit (baseline)Sponsors and contacts
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Source ClinicalTrials.gov