Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement

ConditionHemodynamic
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-80
SponsorAffiliated Hospital of Jiaxing University

About this trial

Compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction, so as to evaluate the feasibility of using the internal jugular vein variability under deep inspiration to guide preoperative fluid infusion.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

age over 60 years; American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ; Surgery with radial artery puncture; Propofol induction;

Disqualifiers

BMI≥30kg/m2; People with short necks; Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure<65mmHg); Previous poorly controlled hypertension; Cardiac insufficiency , EF value<50%; Upper limb deep vein thrombosis; History of radiotherapy or neck surgery; Inability to maintain a supine position for necessary measurements; Mechanical ventilation status or inability to take deep breaths patients; gastrointestinal surgery; Patients allergic to propofol; Restricted fluid intake;

Trial design

Design model

Parallel

Treatments tested in this trial

  • Guiding rehydration

    Behavioral

    Preoperative fluid rehydration was performed according to 421 fluid rehydration principles

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Guiding rehydration groupExperimental treatment 1 intervention
Group B: Conventional rehydration groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

The incidence of a 20% drop in blood pressure after propofol induction

The incidence of a 20% drop in blood pressure after propofol induction

Time frame
1 year

Secondary outcomes

Other outcomes

Sponsors and contacts

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