This study will investigate the feasibility of implementing a time-restricted eating intervention in females with mild cognitive impairment. Targeted therapeutic interventions that improve cognitive impairment and delay onset of ADRD are particularly important for females, who have twice the lifetime risk of developing AD, compared to males.
Postmenopausal Women
Age 45-95
Diagnosis of mild cognitive impairment
Individuals prone to hypoglycemia
Liver disease
Taking medications that affect eating behaviors
Alcohol consumption of >2 drinks per day
Single group
Time-restricted eating
BehavioralSubjects will be educated about the health benefits of time-restricted eating. Each subject will self-select a 10-hour (10hr +/- 1 hr) window aligned with their active phase during which they will consume all daily calories. Subjects will text the time of their first and last daily calories for the duration of the study.
Number of participants adhering to TRE protocol
The times of first and last meals will be collected from participants with an SMS texting system. Adherence defined as minimum 10 hour (+/- 1hr) TRE window 5 days per week.
Click on the lead sponsor to view all of their trials.
Julie Pendergast
Lead sponsor
University of Kentucky
Sponsor institution
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
