The purpose of this study is to demonstrate feasibility, usability, and acceptability of virtual reality (VR)-based cognitive and physical rehabilitation, evaluate adherence, tolerability, and fidelity to the VR intervention and explore preliminary effectiveness of VR-based rehabilitation on cognitive, physical, and functional outcomes.
Clinical diagnosis of MCI (MoCA 18-26) or self-reported subjective cognitive decline (SCD)
Capacity to provide informed consent
Able to provide own transportation to sessions
Speaks and understands English
Uncontrolled seizures or epilepsy
Severe psychiatric illness or active suicidality
Inability to follow instructions or tolerate VR (severe motion sickness)
Cognitive impairment as a result of a known cause (e.g., dementia, stroke, Traumatic Brain Injury (TBI), medications, etc.)
Single group
Virtual Reality (VR) sessions
DeviceParticipants will complete 3 supervised virtual reality (VR) sessions per week for 6 weeks for a total of 18 sessions using either the Real System VR headset or the Oculus Quest 2 VR headset. Each session will last approximately 60 minutes, with time allocated for setup and brief symptom checks.
Feasibility as assessed by the recruitment rate
Feasibility as assessed by the retention rate
Feasibility as assessed by the session completion rate
Usability as assessed by the System Usability Scale (SUS)
The System Usability Scale (SUS) is a validated 10-item questionnaire used to assess participants' perceived usability of the intervention. each rated on a 5-point Likert scale from 1 = Strongly Disagree, 2 = Disagree 3 = Neutral ,4 = Agree, 5 = Strongly Agree. Scores range from 0 to 100, with higher scores indicating greater usability.
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The University of Texas Health Science Center, Houston
Lead sponsor
DPRIT Seed Grant
Collaborator
