Femoral Nerve Mobilization for Patients With Knee Osteoarthritis

ConditionKnee Osteoarthristis

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age50+

SponsorPrince Sattam Bin Abdulaziz University

About this trial

Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality. There is a limited knowledge about using femoral nerve mobilization in treating patients with arthritic changes.

Objectives: This study will be designed to determine the efficacy of adding of femoral nerve mobilization on pain intensity, function, quality of life and central sensitization in patients with knee osteoarthritis Methods: Thirty patients (aged ≥50 years with KO Kellgren-Lawrence grades I-II) will be included in this study: Patients will randomly be assigned into two groups: group A will receive traditional physical therapy while group B will receive femoral nerve mobilization in addition to traditional physical therapy. Three sessions will be performed for four weeks by 3 session /week. Patients will be evaluated for pain intensity using the numerical rating scale (NRS), knee function by WOMAC scale, quality of life by 12-item Short Form Survey questionnaire (SF-12) and central sensitization by the Arabic version of central sensitization inventory (CSI).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients aged 50 years or older, diagnosed with KO according to theAmerican College of Rheumatology's criteria with knee pain, and grade I or II on the Kellgren-Lawrence radiographic scale

Disqualifiers

individuals suffering from chronic conditions considered to be perpetuating factors (e.g., fibromyalgia)

those with conditions causing lower extremity pain

individuals who had taken analgesics within 24 h before evaluations

those who had undergone corticosteroid or local anesthetic infiltration in the year prior to the study or during the follow-up period

Trial design

Design model

Parallel

Treatments tested in this trial

traditional physical therapy
Other intervention
stretching exercises for hamstring, calf muscles and iliotibial band in addition to isotonic exercise for hip extensors and abductors and isometric quadriceps exercise
Femoral nerve mobilization
Other intervention
A physiotherapist guided the patients in performing active mobilization of the femoral nerve. The prescribed method for active neural mobilization involved assuming a prone position supported by the forearms with a slight extension of the spine, flexion of the knee, and extension of the cervical spine. This was followed by performing the opposite movement

Treatment groups

50 Participants

are divided into 2 treatment groups

Group A: Control groupActive comparator 1 intervention

Group B: Neural mobilization groupExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

pain intensity

The pain was assessed by the numerical rating scale (NRS) where zero indicating no pain and 10 indicating maximal pain

Time frame

after 4 weeks

central sensitization

The CSI is a validated questionnaire designed to identify symptoms associated with central sensitization. It has two components: Scale A assesses 25 common symptoms in individuals with central sensitization, resulting in a score ranging from 0 to 100. This score was interpreted as follows: subclinical (0-29), mild (30-39), moderate (40-49), severe (50-59), and extreme (60-100). Scale B, which is not scored, collects information on previous diagnoses of specific diseases

Time frame

after 4 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Prince Sattam Bin Abdulaziz University

Lead sponsor

Source ClinicalTrials.gov

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