About this trial
Our study hypothesizes that fluorescein exposure in diabetic patients with advanced chronic kidney disease results in deterioration of kidney function. It will therefore aim to evaluate the incidence of acute kidney injury induced by fluorescein in diabetic patients with CKD. The objective is to determine the incidence, severity and risk factors associated with this deterioration to improve the care of this specific population.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
>18 years old with type 2 or type 1 diabetes and chronic kidney disease stage 3b to 5 (eGFR<45 mL/min/1.73 m2)
Disqualifiers
Patients who do not give their consent
Patients who are allergic to fluorescein
Patients who are on dialysis
Patients who had fever, vomiting, diarrhea or any dehydration 48 hours before the intervention
Trial design
Single group
Treatments tested in this trial
Fluorescein angiography
Diagnostic testFluorescein angiography
Treatment groups
Trial outcomes
Primary outcomes
Change in serum creatinine
Change in serum creatinine from baseline to day 4
Secondary outcomes
Long-term change in serum creatinine
Change in serum creatinine from baseline to end of the third month
Sponsors and contacts
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