Following the Sound of Music

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-101
SponsorNortheastern University

About this trial

The proposed study will enroll healthy older adult participants to examine the effectiveness of music listening activities to promote hearing and cognition. Participants will be randomized into one of four experimental groups and can expect to participate for up to 21 hours of research distributed over 20 weeks.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age: 60+

No self-reported auditory difficulties and normal or near-normal hearing sensitivity as measured by SRTs.

Should have no more than typical hearing loss for their age and no evidence of dementia.

Fluent in English and/or Spanish

Disqualifiers

Abnormal vision or hearing prohibitive of training

History of seizures, focal brain lesion, or head injury with loss of consciousness

Physical handicap (motor or perceptual) that would impede training procedures

Social, educational or economic hardship prohibitive to training schedule Concurrent enrollment in other cognitive training studies

Trial design

Design model

Parallel

Treatments tested in this trial

  • Music Listening with Attentional prompts

    Behavioral

    Participants will listen to musical excerpts, and guided instructions will be provided to tell the participants what aspect of the music to pay attention to and how to respond. Participants will log responses on an interactive tablet-based interface.

  • Music Listening

    Behavioral

    Participants will listen to musical excerpts and will be provided with guided instructions directing their attention to specific aspects of the music. Participants will report when they perceive a noticeable change in the music (e.g., changes in instrumentation, rhythm, texture, or intensity). Participants will log responses on an interactive tablet-based interface.

  • Tone listening with Attentional prompts

    Behavioral

    Participants will be asked to attend to auditory stimuli and respond to them according to guided instructions. Participants will log responses on an interactive tablet-based interface.

Treatment groups

216 Participants
are divided into 4 treatment groups
Group A: Sound of Music Plus AttentionExperimental treatment 1 intervention
Group B: Sound of MusicExperimental treatment 1 intervention
Group C: Sound of Tones Plus AttentionExperimental treatment 1 intervention
Group D: Business as usual ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Digits-in-Noise Task

The Digits-in-Noise (DIN) test presents trials of three sequential spoken digits against a broad-band, speech-shaped masker. Signal/noise ratio is varied adaptively to track 50% correct. The dependent variable is the threshold noise tolerance in dB. Lower scores indicate better performance.

Time frame
Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
2

Spatial Release From Masking Task

Tests the ability to distinguish speech from competing speech. Collocated condition uses target and two competing maskers all located directly in front of the listener, and spatially separated condition uses two masking sentences sent from 45 degrees to the left and right of center. Sentences are correctly identified as part of a series of test trials in which TMR progressively reduced every two trials. The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified. Lower scores indicate better performance.

Time frame
Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
3

Dichotic Sentence Identification Task

The DSI test simultaneously presents two nonsense sentences, one to each ear. Participants indicate two sentences heard from a list of alternatives. DSI sentences are presented at a comfortable listening level, usually 50 dB above pure-tone average of each ear. The dependent variable is the percentage of sentences correctly identified. Higher scores indicate better performance.

Time frame
Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)

Secondary outcomes

1

Revised Hearing Handicap Inventory for the Elderly (RHHI)

Survey that assesses the perceived level of hearing ability under different environmental or social situations, and participants also self-report ear surgeries or known ear pathologies. The dependent variable is total score (summed). Higher scores indicate greater perceived handicap.

Time frame
Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
2

Speech Recognition Threshold using Coordinate Response Measure

SRT stimuli from the Coordinate Response Measure are sentences that participants hear that contain a color and number (e.g., "Ready Charlie, go to blue three now"). Participants select one of 36 colored/numbered squares that matches the color-number combination of the sentence. The dependent variable is the threshold target-to-masker ratio (TMR) as estimated based on the number of sentences correctly identified as part of a series of 20 test trials in which TMR progressively reduced every two trials. Lower scores indicate better performance.

Time frame
Pre-test (week 1), Mid-test (week 5), Post-test (week 10), Follow-up (week 18)
3

Gap Detection Task

Temporal sensitivity to silent gaps between pairs of brief (4 ms) bandlimited stimuli. The gap duration will start at 6 ms, and be reduced from there using a staircase procedure. The dependent variable is the threshold (in ms) at which participants stop responding accurately. Lower scores indicate better performance.

Time frame
Pre-test (week 1), Post-test (week 10)
4

Spectrotemporal Sensitivity Task

Stimuli are either unmodulated or are spectrotemporally modulated in amplitude using two cycles/octave for the spectral modulation and 4 Hz for the temporal modulation. Modulation depth in decibels (dB) will be adaptively varied to estimate threshold. The dependent variable is the threshold (in dB) at which participants stop responding accurately. Lower scores indicate better performance.

Time frame
Pre-test (week 1), Post-test (week 10)

Other outcomes

1

POMS 2-A

Self report measure assessing current mood states in adults. Participants rate descriptive mood words according to how they feel during the specified assessment timeframe using a 5-point response scale. The dependent variable is Total Mood Disturbance (TMD) score, with higher values indicating greater overall mood disturbance.

Time frame
Pre-test (week 1), Post-test (week 10), Follow-up (week 18)
2

Ryff's Scale of Psychological Well-being Score

Self-report questionnaire that assesses six domains of well-being (self-acceptance, environmental mastery, positive relations, purpose in life, personal growth, and autonomy). Higher scores indicate greater perceived well-being.

Time frame
Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
3

Short Warwick-Edinburgh Mental Wellbeing Scale (SWEMWBS)

A 7-item self-report measure assessing positive mental well-being. Participants rate statements about their thoughts and feelings over the specified assessment period using a 5-point response scale. The dependent variable is the total well-being score, with higher values indicating greater mental well-being.

Time frame
Pre-test (week 1), Follow-up (week 18), Follow-up (week 18)
4

Musicality Survey

Self-report survey of participants' past musical experiences, with items including the Active Engagement, Perceptual Abilities, and Emotions factors from the Goldsmith's Music Sophistication Index, the Absorption factor from the Extended Barcelona Music Reward Questionnaire, and selected items from the Ollen Music Sophistication Index. Higher scores indicate greater self-reported musical involvement and ability.

Time frame
Pre-test (week 1), Follow-up (week 18)

Sponsors and contacts

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