Health TrialsbyHealthPanel

Free Walking Exercise in Obstructive Sleep Apnea Patients With Non-alcoholic Fatty Liver

ConditionsObstructive Sleep ApneaNon-alcoholic Fatty Liver
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-65
SponsorAhram Canadian University

About this trial

Research evaluating the impact of continuous positive airway pressure (CPAP) \& walking exercise on fatigue severity, liver enzymes and sleeping quality in patients with non-alcoholic fatty liver disease who also have obstructive sleep apnea. Forty patients are divided into two groups: twenty patients CPAP and other twenty patients for CPAP and walking program .

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

The body mass index (BMI) < 35 kg/m2.

obstructive sleep apnea patients with fatty liver

Disqualifiers

liver transplantation , alcoholic fatty liver, antipsychotic medications, bariatric surgery; cardiac , renal problem , liver cancer ; pregnancy,orthopedic problems, systemic diseases, respiratory dysfunctions, neurological dysfunctions.

Trial design

Design model

Parallel

Treatments tested in this trial

  • continuous positive airway pressure

    Behavioral

    continuous positive airway pressure therapy for a period of 12 weeks, all patients with in this group are required to utilize the CPAP machine for at least 4 hours each night

  • free walking exercise and continuous positive airway pressure

    Behavioral

    patients will receive continuous positive airway pressure therapy for a period of 12 weeks, all patients with in this group are required to utilize the CPAP machine for at least 4 hours each night. Also, patients will perform walking exercise for 30 mint, daily for 12 weeks

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: continuous positive airway pressure therapyActive comparator 1 intervention
Group B: Free walking & continuous positive airway pressure therapyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Alanine tranaminase

serum hepatic enzyme

Time frame
it will be measured after 12 weeks

Secondary outcomes

1

Asparatate transamianse

serum hepatic enzyme

Time frame
it will be measured after 12 weeks
2

Body mass index

it will be masusured on empty stomach and bladder

Time frame
it will be measured after 12 weeks
3

triglycerodes

it will be meausred in plasma

Time frame
it will be assessed after 12 weeks
4

Pittsiburg sleeping quality index

a questionnaire that wil be used for assessing sleeping quality

Time frame
it will be assessed after 12 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ahram Canadian University

Lead sponsor

Source ClinicalTrials.gov
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