French Cohort of Myocardial Infarction Evaluation
ConditionAcute Myocardial Infarction
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
Over the last two decades, considerable progress has been made in the management of Acute Myocardial Infarction (AMI), both in the acute phase and in monitoring beyond the hospital phase. Nevertheless, the evolution of care practices and their impact on the mid- and long-term prognosis of patients admitted to the intensive care unit for acute myocardial infarction remain relatively little studied exhaustively.
The aim of this study is to assess the profile of AMI patients, their management and follow-up in order to evaluate the relationship between these factors and outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Symptoms compatible with myocardial ischemia
Appearance of pathological Q waves
ST- T changes compatible with myocardial ischemia (ST segment elevation or depression, T-wave inversion)
Written consent.
Disqualifiers
Iatrogenic MI defined as MI occurring within 48h of a therapeutic procedure
AMI diagnosis invalidated in favor of another diagnosis
Trial population
Consecutive eligible (cf eligibility criteria) patients admitted in one of the Intensive Coronary Units participating to the study.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
30,000 Participants
are grouped into 1 trial groupGroup A: Myocardial infarction
Trial outcomes
Primary outcomes
1
In-hospital mortality
In-hospital mortality
Time frame
Through the end of initial hospitalization, an average of 5 days2
In-hospital outcomes
To measure the in-hospital major cardiovascular events : recurrence of AMI, myocardial revascularization, stroke
Time frame
Through the end of initial hospitalization, an average of 5 days3
Lipopretein 1 evolution
To evaluate plasma concentrations of Lpa and its dynamic pattern during hospital index and 3-9 months following hospitalization.
Time frame
9 months after the end of initial hospitalizationSecondary outcomes
1
Cardiovascular outcomes during follow-up
All cause death and Cardiovascular events including non fatal Myocardial Infarction, non fatal stroke, revascularization, hospitalization for other cardiovascular causes including Bleeding leading to hospitalization
Time frame
Up to 20 years2
Non cardiovascular outcomes during follow-up
All cause death and Non-cardiovascular events leading to to hospitalizations
Time frame
Up to 20 years3
Relationship between patients profile and mortality and cardiovascular morbidity outcomes according to management
All cause death and cardiovascular events including non fatal MI, non fatal stroke, revascularization, hospitalization for other cardiovascular causes including Bleeding leading to hospitalization according to patient's management
Time frame
Up to 20 years4
Relationship between patients profile and mortality and non-cardiovascular morbidity outcomes according to management
All cause death and Non-cardiovascular events leading to to hospitalizations according to patient's management
Time frame
Up to 20 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Assistance Publique - Hôpitaux de Paris
Lead sponsor
Novartis
Collaborator
Source ClinicalTrials.gov