One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.
Adults (≥ 18 years old)
Patients intubated and undergoing one-lung ventilation during thoracic surgery
Volume-controlled ventilation mode used intraoperatively
Arterial blood gas data unavailable during one-lung ventilation
Missing demographic data (sex, height, actual weight)
Patient undergoing thoracic surgery requiring intraoperative one-lung ventilation
Cohort
Retrospective
one lung ventilation
Other interventionArterial blood gases during one lung ventilation
Respiratory acidosis
The frequency of respiratory acidosis on arterial blood gases after 20 minutes of mechanical ventilation (pH \< 7.35 and PaCO2 \> 45mmHg) measured by arterial blood gases
Respiratory rate
Respiratory rate set by the doctor, this respiratory rate will be compared to the suggestion of the algorithm
Acid-base disorder
Presence of Respiratory alkalosis define by pH\>7.45 and PaCO2 \< 35 mmHg
Number of participants with hemodynamic shock - hypotension
Requiring \>1L of volume repletion and/or use of amines at \>0.05 mcg/kg/min or norepinephrine equivalent
Hospital length of stay
Recovery room admission through hospital discharge
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