About this trial
The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia. A hypothesized path from the neural processes of social cognition, to social cognition assessed behaviorally, to real-life social interactions is examined. Secondary aims are to compare electrophysiological measures of high vs low level social cognition; to develop assessment methods of real-life behavior; and to increase the ecological validity of schizophrenia research. Much research within the field is devoid of personal meaning and interpersonal context. This project's use of personalized assessment allows for an ecologically valid approach to the social deficits of schizophrenia.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
schizophrenia
schizoaffective disorder
Disqualifiers
diabetes
Hyperthyroidism
severe head trauma
neurological disease
Trial population
Individuals with a diagnosis of schizophrenia will be compared to healthy control participants
Trial design
Case-control
Cross-sectional
Treatments tested in this trial
This is not an intervention study
Other interventionThis is not an intervention study
Treatment groups
Trial outcomes
Primary outcomes
Neurophysiology: EEG
EEG mu suppression paradigm using point-light displays
Neurophysiology: ERP
ERP mentalizing paradigm (perspective taking)
Cognition
Matrics Consensus Cognitive Battery
Negative symptoms: clinician-rated
Positive and Negative Syndrome Scale (PANSS) 2. Objectively assessed using computerized software (FaceReader, PRAAT) of video-taped personal narratives produced by the participants
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: