From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age17-55
SponsorOslo University Hospital

About this trial

The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia. A hypothesized path from the neural processes of social cognition, to social cognition assessed behaviorally, to real-life social interactions is examined. Secondary aims are to compare electrophysiological measures of high vs low level social cognition; to develop assessment methods of real-life behavior; and to increase the ecological validity of schizophrenia research. Much research within the field is devoid of personal meaning and interpersonal context. This project's use of personalized assessment allows for an ecologically valid approach to the social deficits of schizophrenia.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

schizophrenia

schizoaffective disorder

Disqualifiers

diabetes

Hyperthyroidism

severe head trauma

neurological disease

Trial population

Individuals with a diagnosis of schizophrenia will be compared to healthy control participants

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

  • This is not an intervention study

    Other intervention

    This is not an intervention study

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: SZ1 intervention
Group B: HC1 intervention

Trial outcomes

Primary outcomes

1

Neurophysiology: EEG

EEG mu suppression paradigm using point-light displays

Time frame
1 day (when assessed)
2

Neurophysiology: ERP

ERP mentalizing paradigm (perspective taking)

Time frame
1 day (when assessed)
3

Cognition

Matrics Consensus Cognitive Battery

Time frame
1 day (when assessed)
4

Negative symptoms: clinician-rated

Positive and Negative Syndrome Scale (PANSS) 2. Objectively assessed using computerized software (FaceReader, PRAAT) of video-taped personal narratives produced by the participants

Time frame
1 day (when assessed)

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: