From Early Music Audiometry to Tone Audiograms
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7-45
SponsorGuy's and St Thomas' NHS Foundation Trust
About this trial
Hearing tests are crucial for a child's development, but the standard test, Visual Reinforcement Audiometry (VRA), often doesn't work for those with social communication disorders (SCD) and autism spectrum disorder (ASD). A standardised filtering tool has been developed. Understanding how the results from this new music test compare to standard test results, particularly in people with hearing loss, is critical to establishing the fundamental psychoacoustic threshold relationship. This basic science research validates the acoustic methodology before any future clinical diagnostic application can be considered
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged 7 to 45 years old
Able to reliably perform conventional Pure Tone Audiometry
Confirmed stable bilateral hearing loss with a 4-frequency (500, 1000, 2000, 4000 Hz) pure-tone average ≥25 dB HL in the better hearing ear
Disqualifiers
Aged under 7 or over 45 years old
Unable to complete reliable conventional audiometry task mechanics
Satisfactory hearing or purely unilateral hearing loss (4-frequency pure-tone average in better ear <25 dB HL)
Fluctuating or unconfirmed hearing threshold variations
Trial population
Children, teenagers, and adults aged 7 to 45 years with confirmed, stable, permanent bilateral hearing loss (4-frequency pure-tone average ≥25 dB HL in the better hearing ear) who are able to reliably perform pure-tone audiometry. Participants are sampled from the active clinical caseloads at Guy's and St Thomas' NHS Foundation Trust (GSTT) Paediatric Audiology service and CHEAR Ltd.
Trial design
Design model
Other
Time perspective
Cross-sectional
Treatments tested in this trial
Soundfield Behavioral Audiometry
Other interventionSingle 15-minute behavioral soundfield hearing detection task comparing conventional warble tones, narrow-band noise, and band-pass filtered familiar music stimuli (BPF-FMS). Group 1 receives BPF-FMS generated via the baseline filtering algorithm; Group 2 receives BPF-FMS generated via the optimized filtering algorithm
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: Phase 1 Cohort (Initial Filtering Strategy)1 intervention
Group B: Phase 2 Cohort (Optimized Filtering Strategy)1 intervention
Trial outcomes
Primary outcomes
1
Binaural Sound-field Hearing Threshold Concordance (BPF-FMS vs. Warble Tones)
Quantified threshold agreement between band-pass filtered familiar music stimuli and gold-standard warble tones assessed via mean bias, 95% limits of agreement, and the proportion of matching observations falling within ±5 dB and ±10 dB targets
Time frame
At time of testing (Single 15-minute appointment session)Secondary outcomes
1
Absolute Threshold Discrepancy Compared to Narrow-Band Noise
Comparative absolute error variations of BPF-FMS thresholds against Narrow-Band Noise (NBN) thresholds using linear mixed-effects modeling across identical test sound-field frequencies (500, 1000, 2000, and 4000 Hz)
Time frame
At time of testing (Single 15-minute appointment session)Other outcomes
1
Acoustic Signal Recognition Threshold Offset
Evaluation of absolute error threshold differences across three self-reported music profile variants (Familiar vs. Not Familiar vs. Unsure)
Time frame
At time of testing (Single 15-minute appointment session)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Guy's and St Thomas' NHS Foundation Trust
Lead sponsor
London South Bank University
Collaborator
Audio3 Ltd
Collaborator
CHEAR Ltd
Collaborator
Source ClinicalTrials.gov
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