Functional Evaluation in Patients With Urea Cycle Disorders (UCD) During a Driving Task

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-40
SponsorSt. Jude Children's Research Hospital

About this trial

This study is being done to understand how the brain works while people with urea cycle disorder (UCD) perform driving tasks that range from easy to difficult and to look at how that compares to traditional tests of thinking and attention.

Eligibility criteria

Qualifiers

Individuals 16 to 40 years with molecular or biochemical confirmation of a urea cycle disorder.

Healthy individuals will serve as an age and sex matched comparison group. Active driver's license for at least 6 months

Read and understand English. as the tasks have not been validated in other languages

IQ >=70.

Disqualifiers

Skin disease that affects the scalp

Past or present vascular disease

Head trauma with loss of consciousness in the last year or evidence of cognitive impairment due to and persisting after head trauma

Motor movement disorder which may cause excessive movement or impede use of the steering wheel and/or pedal

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

60 Participants
are grouped into 2 trial groups